Q5YVJ4

PR
Gene name
katG
Protein name
Catalase-peroxidase
Names
CP, Peroxidase/catalase
Species
Nocardia farcinica (strain IFM 10152)
KEGG Pathway
nfa:NFA_29500
EC number
1.11.1.21: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5YVJ4

Entry ID Method Resolution Chain Position Source
AF-Q5YVJ4-F1 Predicted AlphaFoldDB

No variants for Q5YVJ4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5YVJ4

No associated diseases with Q5YVJ4

4 regional properties for Q5YVJ4

Type Name Position InterPro Accession
domain Haem peroxidase 94 - 429 IPR002016-1
domain Haem peroxidase 407 - 714 IPR002016-2
binding_site Peroxidases heam-ligand binding site 264 - 274 IPR019793
active_site Peroxidase, active site 100 - 111 IPR019794

Functions

Description
EC Number 1.11.1.21 Peroxidases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVEHPPIGE ANTEPAAGGC PVTGRLRHPL QGGGNHEWWP NQLNLKVLAK NPAEGNPLGD
70 80 90 100 110 120
FDYKAAFNSL DLAAVKADIA EVLTTSQDWW PADFGNYGPL MIRMAWHSAG TYRSSDGRGG
130 140 150 160 170 180
ANTGQQRFAP LNSWPDNGNL DKARRLLWPV KKKYGQNISW ADLMILAGNV ALETMGFKTF
190 200 210 220 230 240
GFAGGRVDVW EPEEDVYWGP EAEWLGDKRY SGERDLENPL AAVQMGLIYV NPEGPNGNPD
250 260 270 280 290 300
PLAAAVDIKD TFGRMGMTVE ETVALIAGGH TFGKTHGAGD AALVGAEPEA APLEQMGLGW
310 320 330 340 350 360
KSSHGTGKGA DAITSGLEVV WTTKPTQWSN DFFEILFGYE WELTKSPAGA NQWVAKDAQP
370 380 390 400 410 420
IIPDPFDPAK KRLPTMLTTD LSLRVDPEME VISRRFKDNP DEFADAFARA WFKLTHRDLG
430 440 450 460 470 480
PVTRYLGPEV PSEVQLWQDP IPAVDHELVD AADIAALKEQ ILASELSISQ LVKTAWAAAS
490 500 510 520 530 540
SFRGSDYRGG ANGGRIRLQP QLGWEVNEPD ELARVIAVLE GIQEQFNAAQ TGNKKVSFAD
550 560 570 580 590 600
LVVLGGVAAV EQAARNAGVA VEVPFTPGRA DTTQELTDPE GFAVLEPKAD GFRNYLGKAN
610 620 630 640 650 660
PLPAEYLLVD KANLLTLTAP EMTVLVGGLR VLNANYQRSP LGVLTETPES LTNDFFVNLL
670 680 690 700 710 720
DMGVVWEPSP ADDGTYVGKD AATGAQKWTG SRVDLLFGSN SVLRSLAEVY ATDDAKPKFV
730
QDFVAAWNKV MNLDRFDLA