Q5XPH7

PR
Gene name
feoB (LEPBI_I0879)
Protein name
Fe(2+) transporter FeoB
Names
Ferrous iron transport protein B
Species
Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
KEGG Pathway
lbi:LEPBI_I0879
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

125-302 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XPH7

Entry ID Method Resolution Chain Position Source
AF-Q5XPH7-F1 Predicted AlphaFoldDB

No variants for Q5XPH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XPH7

No associated diseases with Q5XPH7

7 regional properties for Q5XPH7

Type Name Position InterPro Accession
domain GTP binding domain 6 - 26 IPR006073-1
domain GTP binding domain 27 - 45 IPR006073-2
domain GTP binding domain 73 - 91 IPR006073-3
domain Ferrous iron transport protein B, C-terminal 461 - 512 IPR011640
domain Nucleoside transporter/FeoB GTPase, Gate domain 350 - 443 IPR011642-1
domain Nucleoside transporter/FeoB GTPase, Gate domain 519 - 658 IPR011642-2
domain FeoB-type guanine nucleotide-binding (G) domain 3 - 166 IPR030389

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
GTP binding Binding to GTP, guanosine triphosphate.

1 GO annotations of biological process

Name Definition
iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKEKNIYLVG NPNCGKTTLF NQLTGLNQKT GNFSGVTVEK KEGVVYLPNL ELKITDLPGT
70 80 90 100 110 120
YGLGGIAEDK KIAYEVLLKR KENEVVIYVL DALNLERGLQ FLLQIIDMGV PTLVVLTMKD
130 140 150 160 170 180
VLEKKRIQLD LKKLKHSLGL EIVLVNAKSG EGISELKTLL SKEESYRKQK RLWTWGSKEE
190 200 210 220 230 240
SFLTSLKQKL KITTNEAEFF LSQALKFLNH DPHLQDSRYL NQFPNETKQF LTKELESKPL
250 260 270 280 290 300
QFAYQEEMIH RSILIKKIIS ETIHYPIAIQ GSWEERLDRI FLHPILGFVC FFLLMGLLFQ
310 320 330 340 350 360
SLFSFAEIPM DLIEEGITGL QETIGNVLSD GPLKSLLIEG ILGGVGSVVV FVPQIALLFL
370 380 390 400 410 420
FIGILEESGY LARASFLMDR LMGKFGLSGK SFIPLLSSAA CAVPAILGTR TIENKSDRFT
430 440 450 460 470 480
TIMVSPLIMC SARYPVYILI VGTVFSYPPI FGIFNVQGFV LFSMFFLGMI VSFTFALIFR
490 500 510 520 530 540
KTVFKENASY FVMELPRYNL PSFKSLFFTV YGKVKSFLAT AGQIILYISV ILWFLSHFPA
550 560 570 580 590 600
EYKDNVWKTS PIETSYIGRV GKVMEPAIEP LGFDWKIGIS ILTSFAAREV MVSTLAVLYG
610 620 630 640 650 660
SEEEGEESES LRETLRADKK PDGSPVWTPL TGLSLLLFFA FASQCMSTLA VTKKETGSLL
670 680
WPTVQFLYMT TLAIFTSFLV FQLGKILGFV