Q5XI37
Gene name |
Mrps15 |
Protein name |
28S ribosomal protein S15, mitochondrial |
Names |
MRP-S15, S15mt |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:298517 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5XI37
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5XI37-F1 | Predicted | AlphaFoldDB |
1 variants for Q5XI37
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs105578254 | 58 | V>F | No | EVA |
No associated diseases with Q5XI37
No regional properties for Q5XI37
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5XI37 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial ribosome | A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. |
| mitochondrial small ribosomal subunit | The smaller of the two subunits of a mitochondrial ribosome. |
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8WTC1 | bonsai | 28S ribosomal protein S15, mitochondrial | Drosophila melanogaster (Fruit fly) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLRAAWRALS | SVRVQAVTQA | PVPALRARSS | ASLPSARCGL | QTPSLLNAAR | AYAVQKPVQA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KQDDEPASST | FIKEYKNIIP | NMEKVDDVVK | RILSLEMASR | KEKLKIKREQ | LMNKIAENPE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DYRTLEARIV | ALTVKIRNYE | EHMQKHRKDK | VHKRHLLMSI | DQRKKFLRLL | RQTNYDVFEK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TCKELGVEYA | LPPLHFQRVH | RRFLAKKALC | IQVFQEVQKL | KKQRMALKAA | AAAAKKEKRE |
| 250 | |||||
| RVPENPSNAL | PEKTKEN |