Q5XH12

PR
Gene name
dhx32
Protein name
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32
Names
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:495093
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XH12

Entry ID Method Resolution Chain Position Source
AF-Q5XH12-F1 Predicted AlphaFoldDB

No variants for Q5XH12

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XH12

No associated diseases with Q5XH12

2 regional properties for Q5XH12

Type Name Position InterPro Accession
domain Helicase-associated domain 459 - 564 IPR007502
domain DEAD-box helicase, OB fold 618 - 697 IPR011709

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALSLEAYEQ DIDELISDEK SCCLDVTDSS DVEGDELNDL ELNPFDGLPY SSRFYKLLKE
70 80 90 100 110 120
RETLPIWKIK YDFLEHLAHN QIVVVSAGPK SGKSSQIPQW CAEYCLAGHY QHGAVVCTQA
130 140 150 160 170 180
HKQTAVWLAM RVADEMDVNI GHEVGYIVPF ENCCTSETIL RYCTDEMLRR EMMSNPLLSS
190 200 210 220 230 240
YGVVIIDDVY ERFVSTDVLL SFLKVIAVSR PELKVVIITC PSLSGTLVSY YGNAPLVEAE
250 260 270 280 290 300
NTHSVESVYT TSLPRDYFHS ALRLLFEIHH TKEKGDIVVF LACEEEIKRA YEHIKQEALH
310 320 330 340 350 360
MNPELGELMP IALYPHQSIS DYIPYEELDD NSKNPKRKVV LTTSLGESLI WMKNIFFVID
370 380 390 400 410 420
VGIEKRKVYN TRIRAESLVT QPISKVRAKM RKHILSSSSE GKLFCLYPED FAHEMKPFLT
430 440 450 460 470 480
AKVEECNLIS MVLFLKRMDI AGLAHCDFIN RPDPESLMQA LEDLDYLAAL DNDGNLSEFG
490 500 510 520 530 540
IIMSEFPLDP QLSKSILAAC EFDCVDEMLT LAAMVTAPNC FIDLPPEAKE LDLIGKGKFF
550 560 570 580 590 600
HPEGDHFTLI NIYNEYEQMK RNNASQYDVE KWCQNHCLSF VALEMARAIR NELLDIMRRI
610 620 630 640 650 660
ELPLTGPAFG SDENVTNIKK SLLSGYFMQI ARDVDGLGNY IMLTHKQVGQ LHPDSGFCNS
670 680 690 700 710 720
AKVPEWVLFH EFSVSERSCI RIVSEISPNL FMEFVPPYYF SNLPPSETKD LLQQDQTPDT
730 740
PPTEEPREEE PLHEANDEGT AEQRCIIQ