Q5XGF1

PR
Gene name
cenpn (TEgg003d08.1)
Protein name
Centromere protein N
Names
CENP-N
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:496510
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

172-256 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XGF1

Entry ID Method Resolution Chain Position Source
AF-Q5XGF1-F1 Predicted AlphaFoldDB

No variants for Q5XGF1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XGF1

No associated diseases with Q5XGF1

No regional properties for Q5XGF1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5XGF1

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome, centromere
  • Localizes exclusively in the centromeres
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromosome, centromeric region The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
kinetochore assembly The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDEWIAEFIK RIILKLPFSQ TMTILKAWGF LTDSELQTLT LRYPKDITAT EVVRLCEAKN
70 80 90 100 110 120
ATIDHAAALD FVFNHAFSNK KLWTVYQMSK TSESENDLFD ASEFKLQFKK SIHAVSKNVT
130 140 150 160 170 180
INFKEFGEAL WIRIAWGTHN TRPNQYKATF AVYHSQTPHV FITGLGKACR PLLCQALVIA
190 200 210 220 230 240
SKYSQIQEME LKSRCLESLK DIVFKRFNQP FSSHHSRPHE KALTQKIVDP RVTYENMREK
250 260 270 280 290 300
ERVHHLTRET FGEGPLPKLE LASYKLETMF RAESIMGGNL TAGNEPFRCV VKFSSPHLLE
310 320 330 340
AIRSLAPAGI AEAPISTLLS CIPHKARNSF KITEKRGLHP ASSQPTNF