Q5XF33
Gene name |
CHLI2 (At5g45930, K15I22.13) |
Protein name |
Magnesium-chelatase subunit ChlI-2, chloroplastic |
Names |
Mg-chelatase subunit I-2, Mg-protoporphyrin IX chelatase subunit ChlI-2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G45930 |
EC number |
6.6.1.1: Forming coordination complexes |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5XF33
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5XF33-F1 | Predicted | AlphaFoldDB |
32 variants for Q5XF33
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_18628099_C_T | 2 | A>V | No | 1000Genomes | |
| tmp_5_18628102_C_T | 3 | S>F | No | 1000Genomes | |
| ENSVATH07349515 | 4 | L>V | No | 1000Genomes | |
| tmp_5_18628123_C_T | 10 | S>F | No | 1000Genomes | |
| tmp_5_18628146_A_T | 18 | I>F | No | 1000Genomes | |
| ENSVATH03368314 | 20 | S>C | No | 1000Genomes | |
| tmp_5_18628171_C_T | 26 | S>L | No | 1000Genomes | |
| ENSVATH00713429 | 27 | M>I | No | 1000Genomes | |
| tmp_5_18628177_C_T | 28 | S>F | No | 1000Genomes | |
| tmp_5_18628190_C_A | 32 | F>L | No | 1000Genomes | |
| ENSVATH00713431 | 37 | L>F | No | 1000Genomes | |
| tmp_5_18628316_G_A | 40 | R>K | No | 1000Genomes | |
| ENSVATH12567472 | 45 | P>T | No | 1000Genomes | |
| ENSVATH00713432 | 47 | K>R | No | 1000Genomes | |
| ENSVATH00713433 | 66 | V>I | No | 1000Genomes | |
| ENSVATH12567473 | 75 | K>N | No | 1000Genomes | |
| ENSVATH00713436 | 137 | S>A | No | 1000Genomes | |
| ENSVATH03368324 | 158 | K>R | No | 1000Genomes | |
| ENSVATH00713438 | 164 | E>Q | No | 1000Genomes | |
| tmp_5_18628954_C_T | 216 | L>F | No | 1000Genomes | |
| tmp_5_18629143_A_C | 279 | M>L | No | 1000Genomes | |
| tmp_5_18629209_C_T | 301 | R>C | No | 1000Genomes | |
| ENSVATH03368330 | 305 | N>S | No | 1000Genomes | |
| tmp_5_18629231_A_G | 308 | E>G | No | 1000Genomes | |
| tmp_5_18629230_G_A | 308 | E>K | No | 1000Genomes | |
| ENSVATH00713441 | 312 | T>S | No | 1000Genomes | |
| tmp_5_18629322_A_C | 338 | Q>H | No | 1000Genomes | |
| ENSVATH07349522 | 350 | E>D | No | 1000Genomes | |
| tmp_5_18629446_G_C | 380 | A>P | No | 1000Genomes | |
| ENSVATH03368332 | 384 | G>A | No | 1000Genomes | |
| ENSVATH07349524 | 389 | N>I | No | 1000Genomes | |
| tmp_5_18629563_TA_T,TAA | 419 | T>= | No | 1000Genomes |
No associated diseases with Q5XF33
1 regional properties for Q5XF33
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RAI1-like | 224 - 295 | IPR013961 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.6.1.1 | Forming coordination complexes |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
| magnesium chelatase complex | A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| magnesium chelatase activity | Catalysis of the reaction: ATP + H2O + Mg2+ + protoporphyrin IX = ADP + 3 H+ + Mg-protoporphyrin IX + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| chlorophyll biosynthetic process | The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors. |
| photosynthesis | The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASLLGRSPS | SILTCPRISS | PSSTSSMSHL | CFGPEKLSGR | IQFNPKKNRS | RYHVSVMNVA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TEINSVEQAK | KIDSKESARP | VYPFAAIVGQ | DEMKLCLLLN | VIDPKIGGVM | IMGDRGTGKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TTVRSLVDLL | PEITVVSGDP | YNSDPRDPEC | MGKEVREKVQ | KGEELSVIET | KINMVDLPLG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ATEDRVCGTI | DIEKALTEGV | KAFEPGLLAK | ANRGILYVDE | VNLLDDHLVD | VLLDSAASGW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NTVEREGISI | SHPARFILIG | SGNPEEGELR | PQLLDRFGMH | AQVGTVRDAE | LRVKIVEERA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RFDSNPKEFR | ETYQEEQLKL | QEQITTARSN | LSAVQIDQDL | KVKISKVCAE | LDVDGLRGDM |
| 370 | 380 | 390 | 400 | 410 | |
| VINRAARALA | ALQGRDQVTA | EDVGIVIPNC | LRHRLRKDPL | ESMDSGILVT | EKFYEVFT |