Q5XAE6

PR
Gene name
accB
Protein name
Biotin carboxyl carrier protein of acetyl-CoA carboxylase
Names
BCCP
Species
Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
KEGG Pathway
spa:M6_Spy1482
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

14-116 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5XAE6

Entry ID Method Resolution Chain Position Source
AF-Q5XAE6-F1 Predicted AlphaFoldDB

No variants for Q5XAE6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5XAE6

No associated diseases with Q5XAE6

2 regional properties for Q5XAE6

Type Name Position InterPro Accession
domain Biotin/lipoyl attachment 90 - 166 IPR000089
binding_site Biotin-binding site 122 - 139 IPR001882

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.

1 GO annotations of molecular function

Name Definition
acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.

1 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIQEIKDLM AQFDTSSLRE FLFKTNEGEL IFSKNEQHLN ASISNQEHAV PVPQVQLVPN
70 80 90 100 110 120
STASEASSPA SVKDVPVEEQ PQAESFVAEG DIVESPLVGV AYLAASPDKP PFVAVGDTVK
130 140 150 160
KGQTLVIIEA MKVMNEVPAP CDGVITEILV SNEDVIEFGQ GLVRIK