Q5WL78
Gene name |
ectB (ABC0335) |
Protein name |
Diaminobutyrate--2-oxoglutarate transaminase |
Names |
DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase |
Species |
Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii) |
KEGG Pathway |
bcl:ABC0335 |
EC number |
2.6.1.76: Transaminases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5WL78
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5WL78-F1 | Predicted | AlphaFoldDB |
No variants for Q5WL78
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5WL78 | |||||
No associated diseases with Q5WL78
No regional properties for Q5WL78
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5WL78 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.6.1.76 | Transaminases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| diaminobutyrate-2-oxoglutarate transaminase activity | Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate. |
| diaminobutyrate-pyruvate transaminase activity | Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ectoine biosynthetic process | The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNETMSIFNE | LESEVRSYCR | SFPAVFTKAK | GWKMWDEDGT | EYIDFFAGAG | ALNYGHNDEK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MKRALIDYIA | DDGITHSLDM | ATKPKAAFLK | KLNEVILKPR | KLNYKVMFPG | PTGTNTVESA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LKLARKVTGR | TEIISFTNGF | HGMTIGSLSV | TGNASKRKGA | GIPLTNVVTM | PYDKFGDEEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DTLRYLEQFL | HDNGSGVDIP | AAVILETVQG | EGGINAARME | WLQQLERICK | KYDILMIIDD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VQAGIGRTGT | FFSFEEAGIT | PDIVCLSKSI | GGYGLPLALT | LFKPELDIWA | PGEHNGTFRG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NNHAFITATA | ALSYWEDPSF | EQAIKDKSKK | IHAFLTKLVD | SYPEMDGCVK | GRGFMAGIGS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KVDGLAGKVA | AEAFKRGLIM | ETAGPEDEVF | KLFPPLTISD | EDLEKGFAII | EESVRAVLGV |
| KEPVTT |