Q5WHS1

PR
Gene name
nadA
Protein name
Quinolinate synthase
Names
Species
Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii)
KEGG Pathway
bcl:ABC1549
EC number
2.5.1.72: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5WHS1

Entry ID Method Resolution Chain Position Source
AF-Q5WHS1-F1 Predicted AlphaFoldDB

No variants for Q5WHS1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5WHS1

No associated diseases with Q5WHS1

No regional properties for Q5WHS1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5WHS1

Functions

Description
EC Number 2.5.1.72 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
quinolinate synthetase A activity Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.

1 GO annotations of biological process

Name Definition
NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQVMQPARLP HHYREMSSAE KEARIREAKA FFGNDLLIPG HHYQREDVIQ FADFTGDSLQ
70 80 90 100 110 120
LAQLCGQTSS ANIVFCGVHF MAETADMLTS REQHVILPDL AAGCSMADMA SIAQTERAWE
130 140 150 160 170 180
ALTERFGDTI LPLTYVNSTA EIKAFCGRHG GACVTSSNAK NMVQWAFAQK PRVMFLPDQH
190 200 210 220 230 240
LGRNTAFALG IPLEKMAVWN PHTHELELLP GANIEEIIVI LWKGHCSVHE KFTVEQIKNV
250 260 270 280 290 300
RDRSPHTQVI VHPECTHEVV QAADKAGSTH YIIETLKQAE PGTSWAIGTE MNLVNRLAKQ
310 320 330 340 350 360
HPDKQVFSLH STMCLCLTMN RIDLDHLAWS LDLLREGKRQ FEITVAEDVA AEARTALARM
LATV