Q5UP57

PR
Gene name
MIMI_L593
Protein name
Putative prolyl 4-hydroxylase
Names
4-PH, Procollagen-proline,2-oxoglutarate-4-dioxygenase
Species
Acanthamoeba polyphaga mimivirus (APMV)
KEGG Pathway
vg:9925229
EC number
1.14.11.2: With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

52-185 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q5UP57

Entry ID Method Resolution Chain Position Source

No variants for Q5UP57

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5UP57

No associated diseases with Q5UP57

3 regional properties for Q5UP57

Type Name Position InterPro Accession
domain Oxoglutarate/iron-dependent dioxygenase 128 - 238 IPR005123
domain Prolyl 4-hydroxylase, alpha subunit 61 - 237 IPR006620
domain Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain 132 - 237 IPR044862

Functions

Description
EC Number 1.14.11.2 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Subcellular Localization
  • Virion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
virion component Any constituent part of a virion, a complete fully infectious extracellular virus particle.

3 GO annotations of molecular function

Name Definition
iron ion binding Binding to an iron (Fe) ion.
L-ascorbic acid binding Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
procollagen-proline 4-dioxygenase activity Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTVTIITII VVIIVVILII MVLSKSCVSH FRNVGSLNSR DVNLKDDFSY ANIDDPYNKP
70 80 90 100 110 120
FVLNNLINPT KCQEIMQFAN GKLFDSQVLS GTDKNIRNSQ QMWISKNNPM VKPIFENICR
130 140 150 160 170 180
QFNVPFDNAE DLQVVRYLPN QYYNEHHDSC CDSSKQCSEF IERGGQRILT VLIYLNNEFS
190 200 210 220 230 240
DGHTYFPNLN QKFKPKTGDA LVFYPLANNS NKCHPYSLHA GMPVTSGEKW IANLWFRERK
FS