Q5U528

PR
Gene name
gtpbp10
Protein name
GTP-binding protein 10
Names
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:495388
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

34-115 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5U528

Entry ID Method Resolution Chain Position Source
AF-Q5U528-F1 Predicted AlphaFoldDB

No variants for Q5U528

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5U528

No associated diseases with Q5U528

3 regional properties for Q5U528

Type Name Position InterPro Accession
domain GTP binding domain 150 - 279 IPR006073
domain GTP1/OBG domain 13 - 148 IPR006169
domain OBG-type guanine nucleotide-binding (G) domain 149 - 344 IPR031167

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
  • Found in the dense fibrillar compartment region of the nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVWCCRVLLR KYGNFVDNLR IYVKGGTGGM GLPRLGGQGG NGGDVCLLAK KGVTLKNIKD
70 80 90 100 110 120
KYPHKRFIGG VGVNSSVRAL KGLAGEVCQV EVPPGIVITN EHGVKIGELD KEGDEIRVAR
130 140 150 160 170 180
GGHGGIFKTD FLPSKGQTRV IHLDLKLISD VGLVGFPNAG KSSLLGKISH AKPQVADYAF
190 200 210 220 230 240
TTVKPELGKI MYPDYKQVSV ADLPGLIEGA HYNRGMGHKF LKHIERTKQL LFVVDIAGFQ
250 260 270 280 290 300
LSAITPCRSA FETVQLLILE LQLYKEELLD KPAVLAVNKM DLPNADEKLG ELLKQLENPT
310 320 330 340 350 360
GNLHSLPDEL VPERQIEFKH IVPVSAATGQ GLEDLIGCIR KTIDEQADVQ IQELAQERLQ
370 380
SLHKETPRTV KRNFQTSPRH KHH