Q5U4T8
Gene name |
cenpn-b |
Protein name |
Centromere protein N-B |
Names |
CENP-N-B |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:495435 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5U4T8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5U4T8-F1 | Predicted | AlphaFoldDB |
No variants for Q5U4T8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5U4T8 | |||||
No associated diseases with Q5U4T8
No regional properties for Q5U4T8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5U4T8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromosome, centromeric region | The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| chromosome segregation | The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. |
| kinetochore assembly | The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDEWLAEFIK | RTILKLPFSE | TATILKTWGF | LTESELQTFT | LRYPKEVTAT | EVVRFCEARN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ATLDHAAALD | LVFNHAYSNK | KTWTVYQMSK | RLESENDLFD | ASEFKLQFKK | SIHAVSKNVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| INFKEFGEAL | WIRIAWGTHN | SRPNQYKATF | AVYHSQTPYV | FITGLGKACQ | PLMCQALVIA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKYSQIQEME | LKSRCLESLK | DIVFKRFNQP | FSSHHSKPHE | KALTPNIVDP | RVTYENMREK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DRVYHLTCET | FGEGPLPKLE | LASYKLETMF | KADSAMSGNL | TAVNEPFRCV | VKFSSPHLLE |
| 310 | 320 | 330 | 340 | ||
| AIRSLAPAGI | AEAPISTLLS | CIPHKARNSF | KITEKRSMHP | SSSQPTNV |