Q5SPX1

PR
Gene name
Ccdc157 (Kiaa1656)
Protein name
Coiled-coil domain-containing protein 157
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:216516
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

459-560 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5SPX1

Entry ID Method Resolution Chain Position Source
AF-Q5SPX1-F1 Predicted AlphaFoldDB

45 variants for Q5SPX1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389150266 31 R>H No EVA
rs3389138044 131 G>S No EVA
rs3389136593 161 R>M No EVA
rs1134517412 206 T>N No EVA
rs3389138322 243 Q>L No EVA
rs3389139299 263 G>R No EVA
rs3389133020 295 Q>* No EVA
rs3389115639 305 E>K No EVA
rs213011668 313 G>R No EVA
rs3389103704 319 S>N No EVA
rs3389077341 320 K>N No EVA
rs224119295 320 K>T No EVA
rs3389132978 323 Q>H No EVA
rs262712289 324 A>T No EVA
rs3389103790 327 Q>E No EVA
rs245947092 331 Q>E No EVA
rs3389132941 357 T>I No EVA
rs255357919 366 V>I No EVA
rs235624867 378 I>M No EVA
rs3389142133 394 R>* No EVA
rs235696504 403 Q>R No EVA
rs3389142198 408 Q>* No EVA
rs3389115637 418 G>R No EVA
rs3389139307 419 A>V No EVA
rs3389077333 439 S>I No EVA
rs3389138065 448 Q>E No EVA
rs3389138073 450 K>M No EVA
rs3389142125 457 Q>E No EVA
rs218942557 470 G>R No EVA
rs239221009 496 E>G No EVA
rs3389139383 508 Q>H No EVA
rs3389140483 510 L>M No EVA
rs3389136679 513 E>K No EVA
rs238586414 525 Q>R No EVA
rs1132613623 532 R>Q No EVA
rs3401700187 533 Q>PLPFLQLLQLLP* No EVA
rs3389142158 535 L>V No EVA
rs3389139321 537 E>K No EVA
rs3389140525 543 R>L No EVA
rs3389150268 547 A>S No EVA
rs1133334629 557 A>T No EVA
rs29457831 601 A>P No EVA
rs29415162 666 R>W No EVA
rs26913680 670 G>S No EVA
rs3389115659 673 S>I No EVA

No associated diseases with Q5SPX1

3 regional properties for Q5SPX1

Type Name Position InterPro Accession
domain Cdc37, N-terminal domain 1 - 129 IPR013855
domain Cdc37, C-terminal 288 - 380 IPR013873
domain Cdc37, Hsp90 binding 122 - 284 IPR013874

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A4IFI1 CCDC157 Coiled-coil domain-containing protein 157 Bos taurus (Bovine) PR
Q569K6 CCDC157 Coiled-coil domain-containing protein 157 Homo sapiens (Human) PR
10 20 30 40 50 60
MAHLLGSQAC MDSLRKDLTD LQGTIVDVFS RAGPVRFPSW KFPDRVACDL DMVALLEHYD
70 80 90 100 110 120
HVPGDPEFTQ LSHAVLLELV IDRLLLLLQS CASYLENLSV EQMMPPARAA GPCMSVGLTV
130 140 150 160 170 180
RRFWSNLLRL GLLYQQAVPQ KRANQGEISI TKPTAKGEPA RSPECMTAKF IKPPSPVPGL
190 200 210 220 230 240
PLICQGLQSI PVRVSLRSPG GTSEKTKSVY SQTVETALVP CDACTSVQGS LWEVGKVVIS
250 260 270 280 290 300
LCQSQNLPSS LGQFQKLVKD SLGLKPLPAA TVGHWAAEQS KDLTRLNKHV GALTQLVGPL
310 320 330 340 350 360
RAQLEDAEGQ KDGLRKQVSK LEQALQQEQG QRQRQTEEAE RTLAKCEHDR HQLLTETCDL
370 380 390 400 410 420
KTKVAVLEGD LKQQQKSIQA MEAKAQQLEE EGERRAAAER QVQQLEEQVQ LLAGRLDGAS
430 440 450 460 470 480
QQIRWASTEL DKEKARVDSM VRHQESLQAK QRTLLQQLDC LDQEREELRG SLDEAEAQRS
490 500 510 520 530 540
ELEEQLQSLQ SDREQEQCQL QAQQELLQSL QQEKQDLEQV TTDLQLTISE LRQQLEELKE
550 560 570 580 590 600
RERLLVAFPD LHQPEEAQIQ SSSNVTQDME RQVQANAIRI QVLQEENKRL QSMLTKIREV
610 620 630 640 650 660
AQQGGLKMVP QGQLWSPPYK GIQGATPPAQ AQSAFSGLTG RRQSPGSRTS STGRTHPGGL
670 680 690 700 710
RTSPSRQPGG LPSKFSLGDG SHSASCTQNP IRALARLRRK LSPNRQAGST YQPQERPT