Q5SK65

PR
Gene name
pyrR (TTHA0783)
Protein name
Bifunctional protein PyrR
Names
Species
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
KEGG Pathway
ttj:TTHA0783
EC number
2.4.2.9: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

43-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q5SK65

Entry ID Method Resolution Chain Position Source
1UFR X-ray 260 A A/B/C/D 1-181 PDB
AF-Q5SK65-F1 Predicted AlphaFoldDB

No variants for Q5SK65

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5SK65

No associated diseases with Q5SK65

6 regional properties for Q5SK65

Type Name Position InterPro Accession
repeat WD40 repeat 276 - 313 IPR001680-1
repeat WD40 repeat 326 - 363 IPR001680-2
repeat WD40 repeat 368 - 407 IPR001680-3
repeat WD40 repeat 410 - 447 IPR001680-4
repeat WD40 repeat 490 - 529 IPR001680-5
repeat WD40 repeat 532 - 569 IPR001680-6

Functions

Description
EC Number 2.4.2.9 Pentosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
uracil phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.

2 GO annotations of biological process

Name Definition
DNA-templated transcription termination The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFKAELMNA PEMRRALYRI AHEIVEANKG TEGLALVGIH TRGIPLAHRI ARFIAEFEGK
70 80 90 100 110 120
EVPVGVLDIT LYRDDLTEIG YRPQVRETRI PFDLTGKAIV LVDDVLYTGR TARAALDALI
130 140 150 160 170 180
DLGRPRRIYL AVLVDRGHRE LPIRADFVGK NVPTSRSEVV KVKVEEVDGE DRVELWEREG
A