Q5SHB1
Gene name |
TTHA1819 |
Protein name |
RNA 2',3'-cyclic phosphodiesterase |
Names |
RNA 2',3'-CPDase |
Species |
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) |
KEGG Pathway |
ttj:TTHA1819 |
EC number |
3.1.4.58: Phosphoric diester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q5SHB1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1IUH | X-ray | 250 A | A | 1-198 | PDB |
| AF-Q5SHB1-F1 | Predicted | AlphaFoldDB |
No variants for Q5SHB1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5SHB1 | |||||
No associated diseases with Q5SHB1
2 regional properties for Q5SHB1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Phosphoesterase, HXTX | 7 - 89 | IPR014051-1 |
| domain | Phosphoesterase, HXTX | 103 - 171 | IPR014051-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.4.58 | Phosphoric diester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity | Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. |
| 2'-5'-RNA ligase activity | Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRLFYAVFLP | EEVRAALVEA | QTKVRPFRGW | KPVPPHQLHL | TLLFLGERPE | EELPDYLALG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HRLARLEAPF | RARLRGTGYF | PNEGTPRVWF | AKAEAEGFLR | LAEGLRAGVE | ELLGEEAVRI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PGWDKPFKPH | ITLARRKAPA | PRVPPVLFGL | EWPVEGFALV | RSELKPKGPV | YTVLEKFSLR |
| 190 | |||||
| GEHGREQAQG | PGERPEGD |