Q5SH28

PR
Gene name
TTHA1902 (TT1467)
Protein name
1,4-alpha-glucan branching enzyme TTHA1902
Names
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Branching enzyme, BE
Species
Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
KEGG Pathway
ttj:TTHA1902
EC number
2.4.1.18: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

473-520 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q5SH28

Entry ID Method Resolution Chain Position Source
1UFA X-ray 220 A A 1-520 PDB
3P0B X-ray 135 A A 1-520 PDB
AF-Q5SH28-F1 Predicted AlphaFoldDB

No variants for Q5SH28

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5SH28

No associated diseases with Q5SH28

2 regional properties for Q5SH28

Type Name Position InterPro Accession
domain Glycoside hydrolase family 57, N-terminal domain 5 - 391 IPR004300
domain 1,4-alpha-glucan branching enzyme, C-terminal 426 - 515 IPR015293

Functions

Description
EC Number 2.4.1.18 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
1,4-alpha-glucan branching enzyme activity Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) Catalysis of the reaction: a glucosylated glycogenin = a glycogen.

2 GO annotations of biological process

Name Definition
alpha-glucan biosynthetic process The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
glycogen biosynthetic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARFALVLHA HLPYVRAHGM WPFGEETLYE AMAETYLPLI RVLERLRAEG VEAPFTLGIT
70 80 90 100 110 120
PILAEQLADA RIKEGFWAYA KDRLERAQGD YQRYRGTALE ASARHQVAFW ELTLDHFQRL
130 140 150 160 170 180
SGDLVAAFRK AEEGGQVELI TSNATHGYSP LLGYDEALWA QIKTGVSTYR RHFAKDPTGF
190 200 210 220 230 240
WLPEMAYRPK GPWKPPVEGP PEGVRPGVDE LLMRAGIRYT FVDAHLVQGG EPLSPYGEAA
250 260 270 280 290 300
LGPVESQEAT YHVHELESGL RVLARNPETT LQVWSADYGY PGEGLYREFH RKDPLSGLHH
310 320 330 340 350 360
WRVTHRKADL AEKAPYDPEA AFAKTEEHAR HFVGLLERLA GRHPEGVILS PYDAELFGHW
370 380 390 400 410 420
WYEGVAWLEA VLRLLAQNPK VRPVTAREAV QGPAVRTALP EGSWGRGGDH RVWLNEKTLD
430 440 450 460 470 480
YWEKVYRAEG AMREAARRGV LPEGVLRQAM RELLLLEASD WPFLMETGQA EAYARERYEE
490 500 510
HARAFFHLLK GASPEELRAL EERDNPFPEA DPRLYLFREA