Q5S1V9

PR
Gene name
IL27 (IL27A)
Protein name
Interleukin-27 subunit alpha
Names
IL-27 subunit alpha, IL-27-A, IL27-A, p28
Species
Sus scrofa (Pig)
KEGG Pathway
ssc:493187
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

133-212 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5S1V9

Entry ID Method Resolution Chain Position Source
AF-Q5S1V9-F1 Predicted AlphaFoldDB

No variants for Q5S1V9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5S1V9

No associated diseases with Q5S1V9

No regional properties for Q5S1V9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5S1V9

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Does not seem to be secreted without coexpression of EBI3
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

2 GO annotations of molecular function

Name Definition
cytokine activity The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.
interleukin-27 receptor binding Binding to an interleukin-27 receptor.

3 GO annotations of biological process

Name Definition
inflammatory response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
regulation of T cell proliferation Any process that modulates the frequency, rate or extent of T cell proliferation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGQMADDLGW RLSLLLLSLL LARAGVWGFP RPPGRPPLSL QELQREFKVS LHLARKLLSE
70 80 90 100 110 120
VRVQARHFAE SHLPGVNLDL LPLGEQLPNV SLNFQAWRGL SDPERLCFLS MTLRPFHTLL
130 140 150 160 170 180
GGLGSQGFWT SSERMQLWAI RLDLRDLQQH LRFQVLAAGF NLPGQEEEEN EAGRELLPGA
190 200 210 220 230
PGGPSKPAAQ VSWPRLLYTY QLLHSLELVL SRAMRDFLLL SRAGNPAPAL GFPTPSSPP