Q5RL51

PR
Gene name
Gstcd
Protein name
Glutathione S-transferase C-terminal domain-containing protein
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:67553
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

159-264 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RL51

Entry ID Method Resolution Chain Position Source
AF-Q5RL51-F1 Predicted AlphaFoldDB

40 variants for Q5RL51

Variant ID(s) Position Change Description Diseaes Association Provenance
rs248078354 9 T>M No EVA
rs3388668426 33 T>I No EVA
rs3388663851 65 K>N No EVA
rs3388660497 101 F>Y No EVA
rs3393728761 154 T>N No EVA
rs3393703811 155 I>S No EVA
rs3393642123 158 A>D No EVA
rs3393784606 159 V>G No EVA
rs3388668479 165 E>D No EVA
rs3388654618 169 H>N No EVA
rs3388646285 170 P>S No EVA
rs3388654628 185 S>R No EVA
rs3388659425 204 Q>P No EVA
rs3388646355 211 P>S No EVA
rs3393554339 215 K>M No EVA
rs45648603 220 S>N No EVA
rs219867714 224 A>P No EVA
rs219867714 224 A>T No EVA
rs259855063 234 P>S No EVA
rs3412948877 280 E>G No EVA
rs3388667915 296 H>N No EVA
rs218441600 346 L>F No EVA
rs3388666284 351 R>G No EVA
rs3388665651 373 G>E No EVA
rs3388665686 379 M>K No EVA
rs3388660828 391 F>I No EVA
rs3388660467 398 A>D No EVA
rs30736506 466 S>L No EVA
rs3388660427 486 S>N No EVA
rs3388666578 489 L>P No EVA
rs3388662179 497 I>T No EVA
rs3388660820 578 T>I No EVA
rs262025216 584 P>S No EVA
rs30735210 588 L>F No EVA
rs3388668471 593 C>* No EVA
rs232786635 603 A>T No EVA
rs3388660844 619 P>L No EVA
rs3388663862 626 N>D No EVA
rs3388660850 627 N>S No EVA
rs3388662706 634 L>S No EVA

No associated diseases with Q5RL51

3 regional properties for Q5RL51

Type Name Position InterPro Accession
domain Glutathione S-transferase, C-terminal 283 - 330 IPR004046
domain Glutathione S-transferase, C-terminal-like 137 - 355 IPR010987
domain Methyltransferase domain 425 - 545 IPR025714

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9VJ34 CG10428 Glutathione S-transferase C-terminal domain-containing protein homolog Drosophila melanogaster (Fruit fly) PR
Q8NEC7 GSTCD Glutathione S-transferase C-terminal domain-containing protein Homo sapiens (Human) PR
10 20 30 40 50 60
MKGIKKSPTE ESLYLEYSHQ TEGCIFPLHT SVTLFLLSYC ECKVFNVCLV LTEESTDTSD
70 80 90 100 110 120
TSFLKEALPQ DLEIQVISKQ ALPPIVQNCC LPAVVDQPDV FCRAGLAVVL RHIIQKSYEA
130 140 150 160 170 180
EPSRKEILEL LGFKKTCLKA CAEVSQWTRL CELTIPLAVE NFLQESSEHP PTIPEEILEL
190 200 210 220 230 240
ERKLSEPVRV HNDDKLRRQK LKQQKAAGSE PPSGKGKAKS KASAQKTPKD LAAPSKSLEL
250 260 270 280 290 300
KVAFSKLTVQ EDAAASNREP SHIRKAKAAD LPPLEHVFAE GLYFTLADIV LLPCIHHFLV
310 320 330 340 350 360
IICKKFSEKL EQFPLLTSWY QRIQEVPKVK TAASKCGIYF LYLPELLNSA RKQPVNSDEV
370 380 390 400 410 420
AAVDEQSDPL FIGGPRPTMT KLMEKGIEAM FSPHPCPAWT LDWSSLPAAV SPKEGKMSTD
430 440 450 460 470 480
RALRKQQQLN NLVYLVLNQA KPGDRIVDFC SGGGHVGIVL AHMLPSCQVT LIENKELSLI
490 500 510 520 530 540
RAKKRSDELG LSNIWFIQAN MEYFTGMFNI GVALHACGVA TDMVIEHCIQ TRASFITCPC
550 560 570 580 590 600
CYGFIQNTSK FNFPKSEKFK KTLSYKEHML LCRFADQTAV QLPPERRLIG KQCMGLVDLD
610 620 630
RAAAAGEHGY SVQVISMEPE SCSPKNNMIV GVPL