Q5RJI2
Gene name |
Slc44a5 (Ctl5) |
Protein name |
Choline transporter-like protein 5 |
Names |
Solute carrier family 44 member 5 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:242259 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RJI2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RJI2-F1 | Predicted | AlphaFoldDB |
46 variants for Q5RJI2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs261002827 | 7 | P>H | No | EVA | |
| rs3393896292 | 9 | S>R | No | EVA | |
| rs3388667783 | 54 | W>R | No | EVA | |
| rs3388659747 | 74 | G>D | No | EVA | |
| rs3393848428 | 90 | N>Y | No | EVA | |
| rs3393768993 | 94 | C>* | No | EVA | |
| rs3393768993 | 95 | T>* | No | EVA | |
| rs3388674233 | 104 | Q>* | No | EVA | |
| rs3388665404 | 116 | P>Q | No | EVA | |
| rs259467100 | 129 | N>S | No | EVA | |
| rs3388668168 | 139 | Y>H | No | EVA | |
| rs3388671451 | 148 | K>Q | No | EVA | |
| rs3388666485 | 177 | I>L | No | EVA | |
| rs3388657407 | 185 | G>V | No | EVA | |
| rs245619731 | 189 | P>S | No | EVA | |
| rs3388659681 | 191 | S>I | No | EVA | |
| rs3388659681 | 191 | S>N | No | EVA | |
| rs3388669089 | 193 | M>K | No | EVA | |
| rs3388673705 | 205 | M>L | No | EVA | |
| rs3388659752 | 217 | D>N | No | EVA | |
| rs3388657386 | 244 | T>N | No | EVA | |
| rs3388670060 | 248 | A>G | No | EVA | |
| rs3388673685 | 250 | S>I | No | EVA | |
| rs3388673675 | 256 | L>F | No | EVA | |
| rs3388668166 | 259 | F>V | No | EVA | |
| rs3388666438 | 273 | L>P | No | EVA | |
| rs3388659686 | 280 | I>L | No | EVA | |
| rs3388671488 | 280 | I>M | No | EVA | |
| rs3388650849 | 367 | Y>C | No | EVA | |
| rs3388667812 | 413 | C>S | No | EVA | |
| rs3388670050 | 427 | C>Y | No | EVA | |
| rs3388666837 | 430 | A>E | No | EVA | |
| rs3388670916 | 433 | N>S | No | EVA | |
| rs3388657406 | 460 | W>R | No | EVA | |
| rs3388651350 | 512 | F>L | No | EVA | |
| rs223828622 | 534 | L>V | No | EVA | |
| rs3388651337 | 539 | N>I | No | EVA | |
| rs3388674295 | 567 | A>T | No | EVA | |
| rs3388674285 | 573 | L>I | No | EVA | |
| rs3388673692 | 613 | L>P | No | EVA | |
| rs3388670907 | 618 | V>L | No | EVA | |
| rs30577620 | 626 | F>L | No | EVA | |
| rs265485316 | 635 | D>E | No | EVA | |
| rs6308112 | 680 | L>I | No | EVA | |
| rs3388651348 | 694 | T>S | No | EVA | |
| rs3393842153 | 709 | K>R | No | EVA |
No associated diseases with Q5RJI2
No regional properties for Q5RJI2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RJI2 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| organic cation transmembrane transporter activity | Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| nitrogen compound transport | The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8IWA5 | SLC44A2 | Choline transporter-like protein 2 | Homo sapiens (Human) | PR |
| Q8N4M1 | SLC44A3 | Choline transporter-like protein 3 | Homo sapiens (Human) | PR |
| B0JZD0 | slc44a5 | Choline transporter-like protein 5 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARKRKPPSS | QGDPRRYDPD | FQGPTAKRTC | TDVLCCLIFL | LFILGYVLLG | LLAWAHGDPR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KMAYPTDSQG | HFCGQKGTPN | ENKTVLFYFN | IFRCTSPSMM | LRLQCSTTQI | CVSRCPERFL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TYLDMQFLNK | EDKNYWEYYR | QFCKAKAKPV | ETLRDLLISG | DCPLAVYPSR | PFLQRCIPDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SALNGTWTPG | SRMKFEDGSG | QTRTMLEFRE | AANGISDLIN | ARTIGLKLLE | DYATSWKWIL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IGLTVAMALS | WTFLILLRFT | AGFLFWFFIF | GVLGIIGYGI | WYCFLEYSSI | QQRPQSTFWM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YGFGIQRRVN | MFFHLKETWF | SMMIILSAIE | IIIIIVLIFL | RTRIQVAIIL | LQEGSKAISY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LPSALIYPVL | TFILLSICIS | YWAVTAVFLA | TSGVPIFKVM | VPAGQCIYED | ETCDPEIFPY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TNIPKDCPGA | SCNFAFYGGR | SMYHNYILTF | QVYNLFAFLW | LINFVIALGQ | CALAGAFASY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YWAMKKPDDI | PPYPLFTAFG | RAVRYHTGSL | AFGSLILASV | QMFKVIVEYL | DRRLKKAQNS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AAQFLHCCLQ | CCFWCLEKMV | KFLNRNAYIM | IALYGKNFCE | STRDAFYLLM | RNILKVTVTD |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EVTYFVLLLG | KVLVSGIVGV | LAFLLFTERL | QIIVDGPTTL | NYYWVPFLTL | VFGSYMIAHG |
| 670 | 680 | 690 | 700 | ||
| FFSVYSMCVE | TIFICFLEDL | ERNEGSPSRP | YFVTPALMNI | LLEQGKIKKQ |