Q5RFR6

PR
Gene name
Kiaa0319l
Protein name
Dyslexia-associated protein KIAA0319-like protein
Names
Adeno-associated virus receptor, AAVR
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100127092
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

136-228 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RFR6

Entry ID Method Resolution Chain Position Source
AF-Q5RFR6-F1 Predicted AlphaFoldDB

No variants for Q5RFR6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RFR6

No associated diseases with Q5RFR6

2 regional properties for Q5RFR6

Type Name Position InterPro Accession
conserved_site Intermediate filament protein, conserved site 375 - 383 IPR018039
domain Intermediate filament, rod domain 78 - 389 IPR039008

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasmic granule membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
  • Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein
  • Cell membrane ; Multi-pass membrane protein
  • Traffics from the plasma membrane to the trans-Golgi network
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasmic vesicle A vesicle found in the cytoplasm of a cell.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEKRLGVKPN PASWILSGYY WQTSAKWLRT LYLFYTCFCF SVLWLSTDAS ESRCQQGKTQ
70 80 90 100 110 120
FGVGLRSGGE NHLWLLEGTP SLQSCWAACC QDSACHVFWW LEGMCIQADC SRPQSCRAFR
130 140 150 160 170 180
THSSNSMLMF LKKFQTADDL GFLPEDDVPH LLGLGWNWAS WRQSPPRAAL RPAVSSSDQQ
190 200 210 220 230 240
SLIRKLQKRG SPSEVVTPIV TQHSKVNDSN ELGGLTTSGS AEVHKAITIS SPLTTDLTAE
250 260 270 280 290 300
LPGGPKNVSA QPEIPEGLAT TPSTQQVKSS EKTQIAVPQP VAPSYSYGTP TPQASFQSTS
310 320 330 340 350 360
APYPVIKELV VSAGDSVQIT LPKNEVQLNA YVLQEPPKGE TYTYDWQLIT HPRDYSGEME
370 380 390 400 410 420
GKHSQILKLS KLTPGLYEFK VIVEGQNAHG EGYVNVTVKP EPRKNRPPIA IVSPQFQEIS
430 440 450 460 470 480
LPTTSTVIDG SQSTDDDKIV QYHWEELKGP LREEKISEDT AILKLSKLVP GNYTFSLTVV
490 500 510 520 530 540
DSDGATNSTT ANLTVNKAVD YPPVANAGPN QVITLPQNSI TLFGNQSTDD HGITSYEWSL
550 560 570 580 590 600
SPSSKGKVVE MQGVRTPTLQ LSAMQEGDYT YQLTVTDTIG QQATAQVTVI VQPENNKPPQ
610 620 630 640 650 660
ADAGPDKELT LPVDSTTLDG SKSSDDQKII SYLWEKTQGP DGVQLENANS SIATVTGLQV
670 680 690 700 710 720
GTYVFTLTVK DERNLQSQSS VNVIVKEEIN KPPIAKITGN VVITLPTSTA ELDGSKSSDD
730 740 750 760 770 780
KGIVSYLWTR DEGSPAAGEV LNHSDHHPIL FLSNLVEGTY TFHLKVTDAK GESDTDRTTV
790 800 810 820 830 840
EVKPDPRKNN LVEIILDINV SQLTERLKGM FIRQIGVLLG VLDSDIIVQK IQPYTEQSTK
850 860 870 880 890 900
MVFFVQNEPP HQIFKGHEVA AMLKSELRKQ KADFLIFRAL EINTVTCQLN CSDHGHCDSF
910 920 930 940 950 960
TKRCICDPFW MENFIKVQLR DGESNCEWSV LYVIIATFVI VVALGILSWT VICCCKRQKG
970 980 990 1000 1010 1020
KPKRKSKYKI LDATDQESLE LKPTSRTGIK QKGLVLSSSL MHSESELDSD DAIFTWPDRE
1030 1040
KGKLLHGQNG SVPNGQTPLK ARSPREEIL