Q5RFI6

PR
Gene name
FASTKD5
Protein name
FAST kinase domain-containing protein 5, mitochondrial
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100171471
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-124 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RFI6

Entry ID Method Resolution Chain Position Source
AF-Q5RFI6-F1 Predicted AlphaFoldDB

No variants for Q5RFI6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RFI6

No associated diseases with Q5RFI6

3 regional properties for Q5RFI6

Type Name Position InterPro Accession
domain FAST kinase leucine-rich 430 - 500 IPR010622
domain FAST kinase-like protein, subdomain 2 512 - 602 IPR013579
domain RAP domain 697 - 758 IPR013584

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion matrix, mitochondrion nucleoid
  • Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial nucleoid The region of a mitochondrion to which the DNA is confined.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
ribonucleoprotein granule A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.

1 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.

3 GO annotations of biological process

Name Definition
mitochondrial RNA processing The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
regulation of mitochondrial mRNA stability Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAATLKSLKL LRYQAFCSPS AFGAVRSVSY WNASSTQHGG QDPPGHISLC HSAKKVKNIC
70 80 90 100 110 120
STFSSRRIPT TSSARPGLEF SKTSSSKAST LQLGSPRATG IDEENVEVFD SFENLRVFLQ
130 140 150 160 170 180
LRPEYRVHSY SASETSQLLS VSEGELILHK VRVNQNNLQA QVIVDYLCKL SSLPAEQHPV
190 200 210 220 230 240
LLGSTSFALL CQLSVRKIKL FDTQDLINVL KAFVILGIPH SHSMLDVYET KCCHQVWEMS
250 260 270 280 290 300
VDQLLLVADL WRYIGRKVPR FLNICCSYLN LRWKDLSLSQ LVHLIYVIGE NRQVSQDLMQ
310 320 330 340 350 360
KLESLILKYI DLINLEEVGT ICLGFFKSKT NLSEFVMRKI GDLACADMQH LSSHSLVNIV
370 380 390 400 410 420
KMFRFTHVDH INFMKQIGEI APQRIPSLGV QGVMHLTLYC SALRFLDEGV MNAVAASLPP
430 440 450 460 470 480
RVAQCRSKDV AKILWSFGTL NYKPPNAEEF YSSLINEIHR KMPEFNQYPE HLPTCLLGLA
490 500 510 520 530 540
FLEYFPVELI DFALSPGFVR LAQERTKFDL IKELYTLDGT VVIECPDYRG NRLSTHLQRE
550 560 570 580 590 600
GSELLWYLAE KDMNSKPEFL ETVFLLETML GGPQYVKHHM ILPHTRSSDL EVQLDVNLKP
610 620 630 640 650 660
LPFNREATPA ENVAKLKCEH VGVSLTDDLM NQLLKGKARG HFQGKTESEP GQQHMELENK
670 680 690 700 710 720
AAVPLGGSLR NVADKSGAME MAGLCPPACM QTPRMKLAIQ FTNRNQYCYG SRDLLGLHNM
730 740 750 760
KRRQLARLGY RVVELSYWEW LPLLKRTRLE KLAFLHEKVF TSAL