Q5RFF6

PR
Gene name
CHID1
Protein name
Chitinase domain-containing protein 1
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174208
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RFF6

Entry ID Method Resolution Chain Position Source
AF-Q5RFF6-F1 Predicted AlphaFoldDB

No variants for Q5RFF6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RFF6

No associated diseases with Q5RFF6

2 regional properties for Q5RFF6

Type Name Position InterPro Accession
domain Glycoside hydrolase family 18, catalytic domain 79 - 393 IPR001223
domain Chitinase II 79 - 385 IPR011583

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Lysosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
lysosome A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

1 GO annotations of molecular function

Name Definition
chitin binding Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.

2 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRTLFNLLWL ALACSPVHAT LSKSDAKKAA SKTLLEKSQF SDKPVQERGL VVTDLKAESV
70 80 90 100 110 120
VLEHRSYCSA KARDRHFAGD VLGYVTPWNS HGYDVTKVFG SKFTQISPVW LQLKRRGREM
130 140 150 160 170 180
FEVTGLHDVD QGWMRAVRKH AKGLHIVPRL LFEDWTYDDF RNVLDSEDEI EELSKTVVQV
190 200 210 220 230 240
AKNQHFDGFV VEVWNQLLSQ KRVGLIHMLT HLAEALHQAR LLALLVIPPA ITPGTDQLGM
250 260 270 280 290 300
FTHKEFEQLA PVLDGFSLMT YDYSTAHQPG PNAPLSWVRA CVQVLDPKSK WRSKILLGLN
310 320 330 340 350 360
FYGMDYATSK DAREPVVGAR YIQTLKDHRP RMVWDSQASE HFFEYKKSRS GRHVVFYPTL
370 380 390
KSLQVRLELA RELGVGVSIW ELGQGLDYFY DLL