Q5RFA0
Gene name |
NELFCD (NELFD, TH1L) |
Protein name |
Negative elongation factor D |
Names |
NELF-D, TH1-like protein |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100171526 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RFA0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RFA0-F1 | Predicted | AlphaFoldDB |
No variants for Q5RFA0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RFA0 | |||||
No associated diseases with Q5RFA0
No regional properties for Q5RFA0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RFA0 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGAAPGAIM | DEDYYGSAAE | WGDEADGGQQ | EDDSGEGEDD | AEVQQECLHK | FSTRDYIMEP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SIFNTLKRYF | QAGGSPENVI | QLLSENYTAV | AQTVNLLAEW | LIQTGVEPVQ | VQETVENHLK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SLLIKHFDPR | KADSIFTEEG | ETPAWLEQMI | AHTTWRDLFY | KLAEAHPDCL | MLNFTVKLIS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DAGYQGEITS | VSTACQQLEV | FSRVLRTSLA | TILDGGEENL | EKNLPEFAKM | VCHGEHTYLF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AQAMMSVLAQ | EEQGGSAVRR | IAQEVQRFAQ | EKGHDASQIT | LALGTAASYP | RACQALGAML |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SKGALNPADI | TVLFKMFTSM | DPPPVELIRV | PAFLDLFMQS | LFKPGARINQ | DHKHKYIHIL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AYAASVVETW | KKNKRVSINK | DELKSTSKAV | ETVHNLCCNE | NKGASELVAE | LSTLYQCIRF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PVVAMGVLKW | VDWTVSEPRY | FQLQTDHTPV | HLALLDEIST | CHQLLHPQVL | QLLVKLFETE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| HSQLDVMEQL | ELKKTLLDRM | VHLLSRGYVL | PVVSYIRKCL | EKLDTDISLI | RYFVTEVLDV |
| 550 | 560 | 570 | 580 | ||
| IAPPYTSDFV | QLFLPILEND | SIAGTIKTEG | EHDPVTEFIA | HCKSNFIMVN |