Q5RF58

PR
Gene name
SLC43A2 (LAT4)
Protein name
Large neutral amino acids transporter small subunit 4
Names
L-type amino acid transporter 4, Solute carrier family 43 member 2
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100171558
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

368-438 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RF58

Entry ID Method Resolution Chain Position Source
AF-Q5RF58-F1 Predicted AlphaFoldDB

No variants for Q5RF58

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RF58

No associated diseases with Q5RF58

No regional properties for Q5RF58

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5RF58

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Basolateral cell membrane
  • Located at the basolateral membrane in the small intestine enterocytes, kidney proximal tubule, thick ascending limb and, to a minor extent, of distal convoluted tubule epithelial cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
L-amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPTLATAHR RRWWMACTAV LENLLFSAVL LGWGSLLIML KSEGFYSYLC TEPENVTNGT
70 80 90 100 110 120
VGSTAEPGHG EASWMNGWLS CQAQDEMLNL AFTVGSFLLS AITLPLGIVM DKYGPRKLRL
130 140 150 160 170 180
LGSACFAVSC LLIAYGASKP NALSVLIFIA LALNGFGGMC MTFTSLTLPN MFGDLRSTFI
190 200 210 220 230 240
ALMIGSYASS AVTFPGIKLI YDAGVSFIII LVVWAGCSGL VFLNCFFNWP LEPFPGPEDM
250 260 270 280 290 300
DYSVKVKFSW LGFDHKITGK QFYKQVTTVG RRLSVGSSMR SAKEQVVLQE GHKLCLSTVD
310 320 330 340 350 360
LEVKCQPDAA AAPSFMHSVF SPILLLSLIT MCVTQLRLIF YMGAMNNILK FLVSGDQKTV
370 380 390 400 410 420
GLYTSIFGVL QLLCLLTAPV IDYIMDWRLK ECEDASEEPE EKDANQGEKK KKKRDRQIQK
430 440 450 460 470 480
ITNAMRAFAF TNLLLVGFGV TCLIPNLPLQ ILSFILHTIV RGFIHSAVGG LYAAVYPSTQ
490 500 510 520 530 540
FGSLTGLQSL ISALFALLQQ PLFLAMMGPL QGDPLWVNVG LLLLSLLGFC LPLYLICYRR
550 560
QLERQLQQRQ EDDKLFLKIN GSSNQEAFV