Q5REF6

PR
Gene name
ENTPD7
Protein name
Ectonucleoside triphosphate diphosphohydrolase 7
Names
NTPDase 7
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100190813
EC number
3.6.1.15: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

22-162 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5REF6

Entry ID Method Resolution Chain Position Source
AF-Q5REF6-F1 Predicted AlphaFoldDB

No variants for Q5REF6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5REF6

No associated diseases with Q5REF6

No regional properties for Q5REF6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q5REF6

Functions

Description
EC Number 3.6.1.15 In phosphorus-containing anhydrides
Subcellular Localization
  • Cytoplasmic vesicle membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasmic vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
CTPase activity Catalysis of the reaction: CTP + H2O = CDP + H+ + phosphate. May or may not be coupled to another reaction.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
metal ion binding Binding to a metal ion.
ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.

4 GO annotations of biological process

Name Definition
CTP catabolic process The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.
GTP metabolic process The chemical reactions and pathways involving GTP, guanosine triphosphate.
nucleobase-containing small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
UTP catabolic process The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARISFSYLC PASWYFTVPT VSPFLRQRVA FLGLFFISCL LLLMLIIDFR HWSASLPRDR
70 80 90 100 110 120
QYERYLARVG ELEATDTEDP NLNYGLVVDC GSSGSRIFVY FWPRHNGNPH DLLDIKQMRD
130 140 150 160 170 180
RNSQPVVKKI KPGISAMADT PEHASDYLRP LLSFAAAHVP VKKHKETPLY ILCTAGMRLL
190 200 210 220 230 240
PERKQLAILA DLVKDLPLEF DFLFSQSQAE VISGKQEGVY AWIGINFVLG RFDHEDESDA
250 260 270 280 290 300
EATQELAAGR RRTVGILDMG GASLQIAYEV PTSTSVLPAK QEEAAKILLA EFNLGCDVQH
310 320 330 340 350 360
TEHVYRVYVT TFLGFGGNFA RQRYEDLVLN ETLNKNRLLG QKTGLSPDNP FLDPCLPVGL
370 380 390 400 410 420
TDVVERNSQV LHVRGRGDWV SCRAMLSPLL ARSNTSQASL NGIYQSPIDF NNSEFYGFSE
430 440 450 460 470 480
FFYCTEDVLR IGGRYHGPTF AKAAQDYCGM AWSVLTQRFK NGLFSSHADE HRLKYQCFKS
490 500 510 520 530 540
AWMYQVLHEG FHFPYDYPNL RTAQLVYGRE VQWTLGAILY KTRFLPLRDL RQEGVRQAHG
550 560 570 580 590 600
SWFRLSFVYN HYLFFACILV VLLAIVLYLL RLRRIHHRQT RASAPLDLLW LEEVVPMMGV
QVGP