Q5REC9

PR
Gene name
RAB8B
Protein name
Ras-related protein Rab-8B
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100171739
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

129-207 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5REC9

Entry ID Method Resolution Chain Position Source
AF-Q5REC9-F1 Predicted AlphaFoldDB

No variants for Q5REC9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5REC9

No associated diseases with Q5REC9

1 regional properties for Q5REC9

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 7 - 162 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Lipid-anchor ; Cytoplasmic side
  • Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side
  • Endosome membrane
  • Recruited to phagosomes containing S
  • aureus or Mycobacterium
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
phagocytic vesicle A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
phagocytic vesicle membrane The lipid bilayer surrounding a phagocytic vesicle.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
GDP binding Binding to GDP, guanosine 5'-diphosphate.
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

2 GO annotations of biological process

Name Definition
cell-substrate junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKTYDYLFK LLLIGDSGVG KTCLLFRFSE DAFNTTFIST IGIDFKIRTI ELDGKKIKLQ
70 80 90 100 110 120
IWDTAGQERF RTITTAYYRG AMGIMLVYDI TNEKSFDNIK NWIRNIEEHA SSDVERMILG
130 140 150 160 170 180
NKCDMNDKRQ VSKERGEKLA IDYGIKFLET SAKSSTNVEE AFFTLARDIM TKLNRKMNDS
190 200
NSAGAGGPVK ITENRSKKTS FFRCLLL