Q5RDP8
Gene name |
PACC1 |
Protein name |
Proton-activated chloride channel |
Names |
PAC, Transmembrane protein 206 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100171892 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RDP8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RDP8-F1 | Predicted | AlphaFoldDB |
No variants for Q5RDP8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RDP8 | |||||
No associated diseases with Q5RDP8
No regional properties for Q5RDP8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RDP8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloride channel complex | An ion channel complex through which chloride ions pass. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| pH-gated chloride channel activity | A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| chloride transport | The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIRQERSTSY | QELSEELDQV | VENSELADEQ | DKETVKVQGP | GVLPGLDSES | ASSSIRFSKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CLKNVFPVLL | IFIYLLLMAV | AVFLVYQTIT | DFREKLKHPV | MSVSYKEVDR | YDAPGIALYP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GQAQLLSCKH | HYEVIPPLTS | PGQPGDMNCT | TQRINYTDPF | SNQTVKSALI | VQGPREVKKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELVFLQFRLN | KSSEDFSAID | YLLFSSFQEF | LQSPNRVGFM | QACESAYSSW | KFSGGFRTWV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KMSLVKTKEE | DGREAVEFRQ | ETSVVNYIDQ | RPAAEKSAQL | FFVVFEWKDP | FIQKVQDIIT |
| 310 | 320 | 330 | 340 | ||
| ANPWNTIALL | CGAFLALFKA | AEFAKLSIKW | MIKIRKRYLK | RRGQATSHIS |