Q5RDJ4

PR
Gene name
LINGO1
Protein name
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100171931
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

496-614 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RDJ4

Entry ID Method Resolution Chain Position Source
AF-Q5RDJ4-F1 Predicted AlphaFoldDB

No variants for Q5RDJ4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RDJ4

No associated diseases with Q5RDJ4

18 regional properties for Q5RDJ4

Type Name Position InterPro Accession
domain Leucine-rich repeat N-terminal domain 35 - 69 IPR000372
repeat Leucine-rich repeat 89 - 149 IPR001611-1
repeat Leucine-rich repeat 282 - 303 IPR001611-2
repeat Leucine-rich repeat 306 - 365 IPR001611-3
repeat Leucine-rich repeat, typical subtype 88 - 111 IPR003591-1
repeat Leucine-rich repeat, typical subtype 112 - 135 IPR003591-2
repeat Leucine-rich repeat, typical subtype 136 - 159 IPR003591-3
repeat Leucine-rich repeat, typical subtype 160 - 183 IPR003591-4
repeat Leucine-rich repeat, typical subtype 184 - 207 IPR003591-5
repeat Leucine-rich repeat, typical subtype 208 - 231 IPR003591-6
repeat Leucine-rich repeat, typical subtype 280 - 303 IPR003591-7
repeat Leucine-rich repeat, typical subtype 304 - 327 IPR003591-8
repeat Leucine-rich repeat, typical subtype 328 - 351 IPR003591-9
domain Immunoglobulin subtype 2 431 - 498 IPR003598
domain Immunoglobulin subtype 425 - 509 IPR003599
domain Immunoglobulin-like domain 405 - 507 IPR007110
domain Immunoglobulin I-set 423 - 508 IPR013098
repeat BspA type Leucine rich repeat region 154 - 272 IPR026906

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLAGGVRSMP SPLLACWQPI LLLVLGSVLS GSATGCPPRC ECSAQDRAVL CHRKRFVAVP
70 80 90 100 110 120
EGIPTETRLL DLGKNRIKTL NQDEFASFPH LEELELNENI VSAVEPGAFN NLFNLRTLGL
130 140 150 160 170 180
RSNRLKLIPL GVFTGLSNLT KLDISENKIV ILLDYMFQDL YNLKSLEVGD NDLVYISHRA
190 200 210 220 230 240
FSGLNSLEQL TLEKCNLTSI PTEALSHLHG LIVLRLRHLN INAIRDYSFK RLYRLKVLEI
250 260 270 280 290 300
SHWPYLDTMT PNCLYGLNLT SLSITHCNLT AVPYLAVRHL VYLRFLNLSY NPISTIEGSM
310 320 330 340 350 360
LHELLRLQEI QLVGGQLAVV EPYAFRGLNY LRVLNVSGNQ LTTLEESVFH SVGNLETLIL
370 380 390 400 410 420
DSNPLACDCR LLWVFRRRWR LNFNRQQPTC ATPEFVQGKE FKDFPDVLLP NYFTCRRARI
430 440 450 460 470 480
RDRKAQQVFV DEGHTVQFVC RADGDPPPAI LWLSPRKHLV SAKSNGRLTV FPGGTLEVRY
490 500 510 520 530 540
AQVQDNGTYL CIAANAGGND SMPAHLHVRS YSPDWPHQPN KTFAFISNQP GEGEANSTRA
550 560 570 580 590 600
TVPFPFDIKT LIIATTMGFI SFLGVVLFCL VLLFLWSRGK GNTKHNIEIE YVPRKSDAGI
610
SSADAPRKFN MKMI