Q5RBV0

PR
Gene name
KPNA6
Protein name
Importin subunit alpha-7
Names
Karyopherin subunit alpha-6
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100172333
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RBV0

Entry ID Method Resolution Chain Position Source
AF-Q5RBV0-F1 Predicted AlphaFoldDB

No variants for Q5RBV0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RBV0

No associated diseases with Q5RBV0

9 regional properties for Q5RBV0

Type Name Position InterPro Accession
repeat Armadillo 112 - 196 IPR000225-1
repeat Armadillo 197 - 239 IPR000225-2
repeat Armadillo 242 - 281 IPR000225-3
repeat Armadillo 283 - 323 IPR000225-4
repeat Armadillo 325 - 367 IPR000225-5
repeat Armadillo 367 - 407 IPR000225-6
repeat Armadillo 410 - 450 IPR000225-7
domain Importin-alpha, importin-beta-binding domain 1 - 102 IPR002652
repeat Atypical Arm repeat 464 - 513 IPR032413

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
nuclear import signal receptor activity Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.

1 GO annotations of biological process

Name Definition
protein import into nucleus The directed movement of a protein from the cytoplasm to the nucleus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
METMASPGKD NYRMKSYKNN ALNPEEMRRR REEEGIQLRK QKREQQLFKR RNVELINEEA
70 80 90 100 110 120
AMFDSLLMDS YVSSTTGESV ITREMVEMLF SDDSDLQLAT TQKFRKLLSK EPSPPIDEVI
130 140 150 160 170 180
NTPRVVDRFV EFLKRNENCT LQFEAAWALT NIASGTSQQT KIVIEAGAVP IFIELLNSDF
190 200 210 220 230 240
EDVQEQAVWA LGNIAGDSSV CRDYVLNCSI LNPLLTLLTK STRLTMTRNA VWALSNLCRG
250 260 270 280 290 300
KNPPPEFAKV SPCLPVLSRL LFSSDSDLLA DACWALSYLS DGPNEKIQAV IDSGVCRRLV
310 320 330 340 350 360
ELLMHNDYKV ASPALRAVGN IVTGDDIQTQ VILNCSALPC LLHLLSSPKE SIRKEACWTI
370 380 390 400 410 420
SNITAGNRAQ IQAVIDANIF PVLIEILQKA EFRTRKEAAW AITNATSGGT PEQIRYLVSL
430 440 450 460 470 480
GCIKPLCDLL TVMDSKIVQV ALNGLENILR LGEQEGKRSG SGVNPYCGLI EEAYGLDKIE
490 500 510 520 530
FLQSHENQEI YQKAFDLIEH YFGVEDDDSS LAPQVDETQQ QFIFQQPEAP MEGFQL