Q5RBN0
Gene name |
MIEF1 (MID51, SMCR7L) |
Protein name |
Mitochondrial dynamics protein MID51 |
Names |
Mitochondrial dynamics protein of 51 kDa homolog, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172382 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RBN0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RBN0-F1 | Predicted | AlphaFoldDB |
No variants for Q5RBN0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RBN0 | |||||
No associated diseases with Q5RBN0
1 regional properties for Q5RBN0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Mab-21-like, HhH/H2TH-like domain | 359 - 446 | IPR046906 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial outer membrane | The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial fission | The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. |
| positive regulation of mitochondrial fission | Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. |
| positive regulation of protein targeting to membrane | Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGAGERKGK | KDDNGIGTAI | DFVLSNARLV | LGVGGAAMLG | IATLAVKRMY | DRAISAPTSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TRLSHSGKRS | WEEPNWMGSP | QLLNRDMKTG | LSRSLQTLPT | DSSAFDTDTF | CPPRPKPVAR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGQVDLKKSR | LRMSLQEKLL | PYYRNRAAIP | AGEQARAKQA | AVDICAELRS | FLRAKLPDMP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LRDVYLSGSL | YDDLQVVTAD | HIQLIVPLVL | EQNLWSCIPG | EDTIMNVPGF | FLVRRENPEY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FPRGSSYWDR | CVVGGYLSPK | TVADTFEKVV | AGSINWPAIG | SLLDYVIRPA | PPPEALTLEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QYERDKHLFI | DFLPSVTLGD | TVLVAKPHRL | AQYDNLWRLS | LRPAETARLR | ALDQADSGCR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SLCLKILKAI | CKSTPALGHL | TASQLTNVIL | HLAQEEADWS | PDMLADRFLQ | ALRGLISYLE |
| 430 | 440 | 450 | 460 | ||
| AGVLPSALNP | KVNLFAELTP | EEIDELGYTL | YCSLSEPEVL | LQT |