Q5RBJ6
Gene name |
STRADA (STRAD) |
Protein name |
STE20-related kinase adapter protein alpha |
Names |
STRAD alpha, STE20-related adapter protein |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172403 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RBJ6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RBJ6-F1 | Predicted | AlphaFoldDB |
No variants for Q5RBJ6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RBJ6 | |||||
No associated diseases with Q5RBJ6
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein kinase activator activity | Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. |
| protein kinase activity | Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| activation of protein kinase activity | Any process that initiates the activity of an inactive protein kinase. |
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| protein export from nucleus | The directed movement of a protein from the nucleus into the cytoplasm. |
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFLVSKPER | IRRWVSEKFI | VEGLRDLELF | GEQPPGDTRR | KTNDASSESI | APFSKQEVMG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SFLPEGGCYE | LLTVIGKGFE | DLMTVNLARY | KPTGEYVTVR | RINLEACSNE | MVTFLQGELH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSKLFNHPNI | VPYRATFIAD | NELWVVTSFM | AYGSAKDLIC | THFMDGMNEL | AIAYILQGVL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KALDYIHHMG | YVHRSVKASH | ILISVDGKVY | LSGLRSNLSM | ISHGQRQRVV | HDFPKYSIKV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LPWLSPEVLQ | QNLQGYDAKS | DIYSVGITAC | ELANGHVPFK | DMPATQTLLE | KLNGTVPCLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DTSTIPAEEL | TMSPSRSVAN | SGLSDSLTTS | TPRPSNGDSP | SHPYHRTFSP | HFHHFVEQCL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QRNPDARPSA | STLLNHSFFK | QIKRRASEAL | PELLRPVTPI | TNFEGSQSQD | HSGIFGLVTN |
| 430 | |||||
| LEELEVDDWE | F |