Q5RBB8
Gene name |
SUDS3 (SDS3) |
Protein name |
Sin3 histone deacetylase corepressor complex component SDS3 |
Names |
Suppressor of defective silencing 3 protein homolog |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172453 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RBB8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RBB8-F1 | Predicted | AlphaFoldDB |
No variants for Q5RBB8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RBB8 | |||||
No associated diseases with Q5RBB8
No regional properties for Q5RBB8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RBB8 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| histone deacetylation | The modification of histones by removal of acetyl groups. |
| positive regulation of apoptotic process | Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAAGLLAPA | PAQAGAPPAP | EYYPEEDEEL | ESAEEDERSC | RGRESDEDTE | DASETDLAKH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DEEDYVEMKE | QMYQDKLASL | KRQLQQLQEG | TLQEYQKRMK | KLDQQYKERI | RNAELFLQLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TEQVERNYIK | EKKAAVKEFE | DKKVELKENL | IAELEEKKKM | IENEKLTMEL | TGDSMEVKPI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MTRKLRRRPN | DPVPIPDKRR | KPAPAQLNYL | LTDEQIMEDL | RTLNKLKSPK | RPASPSSPEH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LPATPAESPA | QRFEARIEDG | KLYYDKRWYH | KSQAIYLESK | DNQKLSCVIS | SVGANEIWVR |
| 310 | 320 | ||||
| KTSDSTKMRI | YLGQLQRGLF | VIRRRSAA |