Q5RB75

PR
Gene name
NUDCD3
Protein name
NudC domain-containing protein 3
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174424
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

79-206 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RB75

Entry ID Method Resolution Chain Position Source
AF-Q5RB75-F1 Predicted AlphaFoldDB

1 variants for Q5RB75

Variant ID(s) Position Change Description Diseaes Association Provenance
rs178114237 222 S>R No Ensembl

No associated diseases with Q5RB75

3 regional properties for Q5RB75

Type Name Position InterPro Accession
domain CS domain 185 - 277 IPR007052
domain NudC N-terminal domain 9 - 67 IPR025934
domain NudC domain-containing protein 3, p23 domain 184 - 285 IPR037905

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasmic dynein complex Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
cilium assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
protein localization to pericentriolar material A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEPGAAELYD QALLGILQHV GNVQDFLRVL FGFLYRKTDF YRLLRHPSDR MGFPPGAAQA
70 80 90 100 110 120
LVLQVFKTFD HMARQDDEKR RQELEEKIRR KEEEEAKTVS AAAAEKEPVP VPVQEIEIDS
130 140 150 160 170 180
TTELGGRQEV EKVQPPGPVK EMAHGSLEAE APGAVAGAAE VPREPPVLPR IQEQFQKNPD
190 200 210 220 230 240
SYNGAVRENY TWSQDYTDLE VRVPVPKHVV KGKQVSVALS SSSIRVAMLE ENGERVLMEG
250 260 270 280 290 300
KLTHKINTES SLWSLEPGKC VLVNLSKVGE YWWNAILEGE EPIDIDKINK ERSMATVDEE
310 320 330 340 350 360
EQAVLDRLTF DYHQKLQGKP QSHELKVHEM LKKGWDAEGS PFRGQRFDPA MFNISPGAVQ
F