Q5RAV6

PR
Gene name
RAB6A
Protein name
Ras-related protein Rab-6A
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100172563
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

144-208 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5RAV6

Entry ID Method Resolution Chain Position Source
AF-Q5RAV6-F1 Predicted AlphaFoldDB

No variants for Q5RAV6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5RAV6

No associated diseases with Q5RAV6

1 regional properties for Q5RAV6

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 13 - 169 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Lipid-anchor
  • Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Peripheral membrane protein
  • BICD2 facilitates its targeting to Golgi apparatus membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

3 GO annotations of biological process

Name Definition
protein localization to Golgi apparatus A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR
70 80 90 100 110 120
TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNVNS FQQTTKWIDD VRTERGSDVI
130 140 150 160 170 180
IMLVGNKTDL ADKRQVSIEE GERKAKELNV MFIETSAKAG YNVKQLFRRV AAALPGMEST
190 200
QDRSREDMID IKLEKPQEQP VSEGGCSC