Q5RAL3
Gene name |
GRM3 |
Protein name |
Metabotropic glutamate receptor 3 |
Names |
mGluR3 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172627 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RAL3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RAL3-F1 | Predicted | AlphaFoldDB |
No variants for Q5RAL3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RAL3 | |||||
No associated diseases with Q5RAL3
No regional properties for Q5RAL3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RAL3 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
| glutamate receptor activity | Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKMLTRLQVL | TLALFSKGFL | LSLGDHNFLR | REIKIEGDLV | LGGLFPINEK | GTGTEECGRI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NEDRGIQRLE | AMLFAIDEIN | KDDYLLPGVE | LGVHILDTCS | RDTYALEQSL | EFVRASLTKV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEAEYMCPDG | SYAIQENIPL | LIAGVIGGSY | SSVSIQVANL | LRLFQIPQIS | YASTSAKLSD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSRYDYFART | VPPDFYQAKA | MAEILRFFNW | TYVSTVASEG | DYGETGIEAF | EQEARLRNIC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IATAEKVGRS | NIRKSYDSVI | RELLQKPNAR | VVVLFMRSDD | SRELIAAASR | ANASFTWVAS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DGWGAQESII | KGSEHVAYGA | ITLELASQPV | RQFDRYFQSL | NPYNNHRNPW | FRDFWEQKFQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CSLQNKRNHR | RVCDKHLAID | SSNYEQESKI | MFVVNAVYAM | AHALHKMQRT | LCPNTTKLCD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AMRILDGKKL | YRDYLLKINF | TAPFNPNKDA | DSIVKFDTFG | DGMGRYNVFN | FQNVGGKYSY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LKVGHWAETL | SLDVDSIHWS | RNSVPTSQCS | DPCAPNEMKN | MQPGDVCCWI | CIPCEPYEYL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ADEFTCMDCG | PGQWPTADLT | GCYDLPEDYI | RWEDAWVIGP | VTIACLGFMC | TCMVVTVFIK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HNNTPLVKAS | GRELCYILLF | GVGLSYCMTF | FFIAKPSPVI | CALRRLGLGS | SFAICYSALL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TKTNCIARIF | DGVKNGAQRP | KFISPSSQVF | ICLGLILVQI | VMVSVWLILE | APGTRRYTLA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EKRETVILKC | NVKDSSMLIS | LTYDVILVIL | CTVYAFKTRK | CPENFNEAKF | IGFTMYTTCI |
| 790 | 800 | 810 | 820 | 830 | 840 |
| IWLAFLPIFY | VTSSDYRVQT | TTMCISVSLS | GFVVLGCLFA | PKVHIILFQP | QKNVVTHRLH |
| 850 | 860 | 870 | |||
| LNRFSVSGTG | TTYSQSSAST | YVPTVCNGRE | VLDSTTSSL |