Q5RAG3
Gene name |
ZER1 (ZYG11BL) |
Protein name |
Protein zer-1 homolog |
Names |
Zyg-11 homolog B-like protein |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172661 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RAG3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RAG3-F1 | Predicted | AlphaFoldDB |
No variants for Q5RAG3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5RAG3 | |||||
No associated diseases with Q5RAG3
No regional properties for Q5RAG3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5RAG3 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| Cul2-RING ubiquitin ligase complex | A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. |
| protein quality control for misfolded or incompletely synthesized proteins | The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASDTPESLM | ALCTDFCLRN | LDGTLGYLLD | KETLRLHPDI | FLPSEICDRL | VNEYVELVNA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ACNFEPHESF | FSLFSDPRST | RLTRIHLRED | LVQDQDLEAI | RKQDLVELYL | TNCEKLSAKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LQTLRSFSHT | LVSLSLFGCT | NIFYEEENPG | GCEDEYLVNP | TCQVLVKDFT | FEGFSRLRFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NLGRMIDWVP | VESLLRPLNS | LAALDLSGIQ | TSDAAFLTQW | KDSLVSLVLY | NMDLSDDHIR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIVQLHKLRH | LDISRDRLSS | YYKFKLTREV | LSLFVQKLGN | LMSLDISGHM | ILENCSISKM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEEAGQTSIE | PSKSSIIPFR | ALKRPLQFLG | LFENSLCRLT | HIPAYKVSGD | KNEEQVLNAI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EAYTEHRPEI | TSRAINLLFD | IARIERCNQL | LRALKLVITA | LKCHKYDRNI | QVTGSAALFY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LTNSEYRSEQ | SVKLRRQVIQ | VVLNGMESYQ | EVTVQRNCCL | TLCNFGIPEE | LEFQYRRVNE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LLLSILNPTR | QDESIQRIAV | HLCNALVCQV | DNDHKEAVGK | MGFVVTMLKL | IQKKLLDKIC |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DQVMEFSWSA | LWNITDETPD | NCEMFLNFNG | MKLFLDCLKE | FPEKQELHRN | MLGLLGNVAE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| VKELRPQLMT | SQFISVFSNL | LESKADGIEV | SYNACGVLSH | IMFDGPEAWG | VCEPQREEVE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ERMWAAIQSW | DINSRRNINY | RSFEPILRLL | PQGISPVSQH | WATWALYNLV | SVYPDKYCPL |
| 730 | 740 | 750 | 760 | ||
| LIKEGGMPLL | RDIIKMATAR | QETKEMARKV | IEHCSNFKEE | NMDTSR |