Q5RAE6
Gene name |
ZNF24 |
Protein name |
Zinc finger protein 24 |
Names |
|
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172674 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5RAE6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5RAE6-F1 | Predicted | AlphaFoldDB |
1 variants for Q5RAE6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs174033007 | 159 | E>D | No | Ensembl |
No associated diseases with Q5RAE6
5 regional properties for Q5RAE6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SCAN domain | 48 - 160 | IPR003309 |
| domain | Zinc finger C2H2-type | 251 - 278 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 279 - 306 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 307 - 334 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 335 - 362 | IPR013087-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription activator activity, RNA polymerase II-specific | A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II. |
| identical protein binding | Binding to an identical protein or proteins. |
| metal ion binding | Binding to a metal ion. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| myelination | The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAQSVEEDS | ILIIPTPDEE | EKILRVKLEE | DPDGEEGSSI | PWNHLPDPEI | FRQRFRQFGY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QDSPGPREAV | SQLRELCRLW | LRPETHTKEQ | ILELVVLEQF | VAILPKELQT | WVRDHHPENG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEAVTVLEDL | ESELDDPGQP | VSLRRRKREV | LVEDMVSQEE | AQGLPSSELD | AVENQLKWAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WELHSLRHCD | DDGRTENGAL | APKQELPSAV | ESHEVPGTLN | MGVPQIFKYG | ETCFPKGRFE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RKRNPSRKKQ | HICDECGKHF | SQGSALILHQ | RIHSGEKPYG | CVECGKAFSR | SSILVQHQRV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HTGEKPYKCL | ECGKAFSQNS | GLINHQRIHT | GEKPYECVQC | GKSYSQSSNL | FRHQRRHNAE |
| KLLNVVKV |