Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R9U8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R9U8-F1 | Predicted | AlphaFoldDB |
No variants for Q5R9U8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R9U8 | |||||
No associated diseases with Q5R9U8
9 regional properties for Q5R9U8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Thioredoxin domain | 132 - 259 | IPR013766-1 |
| domain | Thioredoxin domain | 268 - 378 | IPR013766-2 |
| domain | Thioredoxin domain | 376 - 504 | IPR013766-3 |
| conserved_site | Thioredoxin, conserved site | 295 - 313 | IPR017937-1 |
| conserved_site | Thioredoxin, conserved site | 416 - 434 | IPR017937-2 |
| domain | Protein disulfide-isomerase A5, N-terminal TRX-like b domain | 26 - 137 | IPR041865 |
| domain | Protein disulfide-isomerase A5, TRX (a) domain | 150 - 254 | IPR046374-1 |
| domain | Protein disulfide-isomerase A5, TRX (a) domain | 275 - 377 | IPR046374-2 |
| domain | Protein disulfide-isomerase A5, TRX (a) domain | 396 - 499 | IPR046374-3 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| double-stranded DNA binding | Binding to double-stranded DNA. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA geometric change | The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. |
| DNA-templated transcription termination | The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
| termination of mitochondrial transcription | A transcription termination process that completes the production of a primary mitochondrial transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQSLSLGQTS | ISKGLNYLTI | MAPGNLWHMR | NNFLFGSRCW | MTRFSAENIF | KSVSFRLFGV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KCHNTDSEPL | KNEDLLKNLL | TMGVDIDMAR | KRQPGVFHRM | ITNEQDLKMF | LLSKGASKEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IASIISRYPR | AITRTPENLS | KRWDLWRKIV | TSDLEIVNIL | ERSPESFFRS | NNNLNLENNI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KFLYSVGLTR | KCLCRLLTNA | PRTFSNSLDL | NKQMVEFLQA | AGLSLGHNDP | ADFVRKIILK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TLYLIQSTKR | VKANIEFLRS | TFNLNSEELL | VLICGPGAEI | LDLSNDYARR | SYANIKEKLF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SLGCTEEEVQ | KFVLSYPDVI | FLAEKKFNDK | IDCLMEENIS | ISQIIENPRV | LDSSISTLKS |
| 370 | 380 | 390 | |||
| RIKELVNAGC | NLSTLNITLL | SWSKKRYEAK | LKKLSRFA |