Q5R9U1

PR
Gene name
SGCB
Protein name
Beta-sarcoglycan
Names
Beta-SG
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100172796
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R9U1

Entry ID Method Resolution Chain Position Source
AF-Q5R9U1-F1 Predicted AlphaFoldDB

1 variants for Q5R9U1

Variant ID(s) Position Change Description Diseaes Association Provenance
rs176414420 205 S>A No Ensembl

No associated diseases with Q5R9U1

5 regional properties for Q5R9U1

Type Name Position InterPro Accession
domain TRAM domain 400 - 466 IPR002792
domain Elp3/MiaA/NifB-like, radical SAM core domain 162 - 389 IPR006638
domain Radical SAM 158 - 397 IPR007197
domain Methylthiotransferase, N-terminal 31 - 141 IPR013848
domain RimO, TRAM domain 403 - 464 IPR041582

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane, sarcolemma ; Single-pass type II membrane protein
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
sarcoglycan complex A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.
sarcolemma The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cardiac muscle cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.
muscle organ development The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
vascular associated smooth muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAAAAAAAA EQQSSNGPVK KSMREKAVER RNVNKEHNSN FKAGYIPIDE DRLHKTGLRG
70 80 90 100 110 120
RKGNLAICVI ILLFILAVIN LIITLVIWAV IRIGPNGCDS MEFHESGLLR FKQVSDMGVI
130 140 150 160 170 180
HPLYKSTVGG RRNENLVITG NNQPIVFQQG TTKLSVENNK TSITSDIGMQ FFDPRTQNIL
190 200 210 220 230 240
FSTDYETHEF HLPSGVKSLN VQKASTERIT SNATSDLNIK VDGRAIVRGN EGVFIMGKTI
250 260 270 280 290 300
EFHMGGNMEL KAENSIILNG SVMVSTTRLP SSSSGDQLGS GDWVRYKLCM CADGTLFKVQ
310
VTSQNMGCQI SDNPCGNTH