Q5R9T9
Gene name |
GBP6 |
Protein name |
Guanylate-binding protein 6 |
Names |
GTP-binding protein 6, GBP-6, Guanine nucleotide-binding protein 6 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172797 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R9T9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R9T9-F1 | Predicted | AlphaFoldDB |
No variants for Q5R9T9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R9T9 | |||||
No associated diseases with Q5R9T9
4 regional properties for Q5R9T9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Guanylate-binding protein/Atlastin, C-terminal | 283 - 579 | IPR003191 |
| domain | Guanylate-binding protein, N-terminal | 18 - 280 | IPR015894 |
| domain | GB1/RHD3-type guanine nucleotide-binding (G) domain | 35 - 277 | IPR030386 |
| domain | Guanylate-binding protein, C-terminal | 289 - 579 | IPR037684 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic vesicle | A vesicle found in the cytoplasm of a cell. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to interferon-gamma | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far. |
| defense response to bacterium | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
| immune response | Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESGPKMLAP | ICLVENNNEQ | LLVNQQAIQI | LEKISQPVVV | VAIVGLYRTG | KSYLMNHLAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QNHGFPLGST | VQSETKGIWM | WCVPHPSKPN | HTLVLLDTEG | LGDVEKGDPK | NDSWIFALAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLCSTFIYNS | MSTINHQALE | QLHYVTELTE | LIKAKSSPRP | DGVDDSTEFV | SFFPDFIWTV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RDFTLELKLN | GHPITEDEYL | ENALKLIQGN | NPRVQTSNLP | RECIRRFFPK | RKCFIFDRPT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NDKDLLANIE | KVSEKQLDPK | FQEQTNIFSS | YIFTHARTKT | LREGIIVTGN | RLGTLAVTYV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EAVNSGAVPC | LENAVITLAQ | RENSAAVQRA | ADYYSQQMAQ | RVKFPTDTLQ | ELLDMHAACE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| REAIAIFMEH | SFKDENQEFQ | KKFMETTMNK | KGDFLLQNEE | SSVQYCQAKL | NELSKGLMES |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ISAGSFSVPG | GHKLYMETKE | RIEQDYWQVP | RKGVKAKEVF | QRFLESQVVI | EESILQSDKA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LTDREKAVAV | DRAKKEAAEK | EQELLKQKLQ | EQQQQMEAQD | KSLKENIAQL | KQKLQMEREQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LLREQIMMLE | HTQKVQNDWL | HEGFKKKYEE | MNAEISQFKR | MIDITKNDDT | PWIARTLDKL |
| 610 | 620 | 630 | |||
| ADELTAVLSA | PAKLIGHGVK | GVSSLFKKHK | LPF |