Q5R9I9

PR
Gene name
NACA
Protein name
Nascent polypeptide-associated complex subunit alpha
Names
NAC-alpha, Alpha-NAC
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100172857
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R9I9

Entry ID Method Resolution Chain Position Source
AF-Q5R9I9-F1 Predicted AlphaFoldDB

No variants for Q5R9I9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R9I9

No associated diseases with Q5R9I9

2 regional properties for Q5R9I9

Type Name Position InterPro Accession
domain Nascent polypeptide-associated complex NAC domain 70 - 135 IPR002715
domain Nascent polypeptide-associated complex subunit alpha-like, UBA domain 176 - 214 IPR044034

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nascent polypeptide-associated complex A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID
70 80 90 100 110 120
EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY
130 140 150 160 170 180
IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETDVEVKD
190 200 210
IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM