Q5R9D1
Gene name |
CASTOR1 |
Protein name |
Cytosolic arginine sensor for mTORC1 subunit 1 |
Names |
GATS-like protein 3 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172893 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R9D1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R9D1-F1 | Predicted | AlphaFoldDB |
No variants for Q5R9D1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R9D1 | |||||
No associated diseases with Q5R9D1
No regional properties for Q5R9D1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5R9D1 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| arginine binding | Binding to 2-amino-5-(carbamimidamido)pentanoic acid. |
| protein sequestering activity | Binding to a protein to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to L-arginine | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus. |
| negative regulation of TORC1 signaling | Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MELHILEHRV | RVLSVARPGL | WLYTHPLIKL | LFLPRRSRCK | FFSLTETPED | YTLMVDEEGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KELPPSEFLQ | VAEATWLVLN | VSSHSGAAVQ | AAGVTKIARS | VIAPLAEHHV | SVLMLSTYQT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DFILVREQDL | SVVIHTLAQE | FDIYREVGGE | PVPVTRDDFS | NGFPRTQHGP | SPTVHPIQSP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QNRFCVLTLD | PETLPAIATT | LIDVLFYSHR | TPKEAASSSP | EPSSITFFAF | SLIEGYISIV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MDAETQKKFP | SDLLLTSSSG | ELWRMVRIGG | QPLGFDECGI | VAQIAGPLAA | ADISAYYIST |
| 310 | 320 | ||||
| FNFDHALVPE | DGIGSVIEVL | QRRQEGLAS |