Q5R903

PR
Gene name
SNX14
Protein name
Sorting nexin-14
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100172967
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

228-308 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R903

Entry ID Method Resolution Chain Position Source
AF-Q5R903-F1 Predicted AlphaFoldDB

No variants for Q5R903

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R903

No associated diseases with Q5R903

6 regional properties for Q5R903

Type Name Position InterPro Accession
domain Phox homology 515 - 638 IPR001683
domain Phox-associated domain 78 - 252 IPR003114
domain Sorting nexin, C-terminal 755 - 858 IPR013937
domain RGS domain 284 - 416 IPR016137
domain Sorting nexin-14, PX domain 512 - 634 IPR037436
domain SNX14, RGS domain 288 - 414 IPR037892

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell projection, dendrite
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
dendrite A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol-3,5-bisphosphate binding Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIFWSFVAGV VTFYCSLGPD SLLPNIFFTI KYKPKQLGLQ ELFPQGHSCA VCGKVKCKRH
70 80 90 100 110 120
RPSLLLENYQ PWLDLKISSK VDASLSEVLE LVLENFVYPW YRDVTDDESF VDELRITLRF
130 140 150 160 170 180
FASVLIRRIH KVDIPSIITK KLLKAAMKHI EVIVKARQKV KNTEFLQQAA LEEYGPELHV
190 200 210 220 230 240
ALRSRRDELH YLRKLTELLF PYILPPKATD CRSLTLLIRE ILSGSVFLPS LDFLADPDTV
250 260 270 280 290 300
NHLLIIFIDD SPPEKATEPA SPLVPFLQKF AEPRNKKPSV LKLELKQIRE QQDLLFRFMN
310 320 330 340 350 360
FLKQEGAVHV LQFCLTVEEF NDRILRPELS NDEMLSLHEE LQKIYKTYCL DESIDKIRFD
370 380 390 400 410 420
PFIVEEIQRI AEGPYIDVVK LQTMRCLFEA YEHVLSLLEN VFTPMFCHSD EYFRQLLRGA
430 440 450 460 470 480
ESPTRNSKLN RGSLSLDDFR NTQKRGESFG ISRIGSKIKG VFKSTTMEGA MLPNYGVAEG
490 500 510 520 530 540
EDDFIEEGIV VMEDDSPVEA VSTPNTPRNL AAWKISIPYV DFFEDPSSER KEKKERIPVF
550 560 570 580 590 600
CIDVERNDRR AVGHEPEHWS VYRRYLEFYV LESKLTEFHG TFPDAQLPSK RIIGPKNYEF
610 620 630 640 650 660
LKSKREEFQE YLQKLLQHPE LSNSQLLADF LSPNGGETQF LDKILPDVNL GKIIKSVPGK
670 680 690 700 710 720
LMKEKGQHLE PFIMNFINSC ESPKPKPSRP ELTILSPTSE NNKKLFNDLF KNNANRAENT
730 740 750 760 770 780
ERKQNQNYFM EVMTVEGVYD YLMYVGRVVF QVPDWLHHLL MGTRILFKNT LEMYTDYYLQ
790 800 810 820 830 840
CKLEQLFQEH RLVSLITLLR DAIFCENTEP RSLQDKQKGA KQTFEEMMNY IPDLLVKCIG
850 860 870 880 890
EETKYESIRL LFDGLQQPVL NKQLTYVLLD IVIQELFPEL NKVQKEVTSV TSWM