Q5R8W8
Gene name |
PTCD3 (MRPS39) |
Protein name |
Pentatricopeptide repeat domain-containing protein 3, mitochondrial |
Names |
28S ribosomal protein S39, mitochondrial, MRP-S39 |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100172990 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R8W8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R8W8-F1 | Predicted | AlphaFoldDB |
No variants for Q5R8W8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R8W8 | |||||
No associated diseases with Q5R8W8
2 regional properties for Q5R8W8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Pentatricopeptide repeat | 254 - 297 | IPR002885-1 |
| repeat | Pentatricopeptide repeat | 331 - 382 | IPR002885-2 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ribosomal small subunit binding | Binding to a small ribosomal subunit. |
| rRNA binding | Binding to a ribosomal RNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
| regulation of translation | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGVSAVRWL | GLRSRLGQPL | TGRRAGLCKQ | ARSCRFYSGS | ATLSKVEGTD | ITGIEEVVIP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KKKTWDKVAV | LQALASTVNR | DTTSVPYVFQ | DDPYLIPASS | LESRLFLLAK | KSGENVAKFI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| INSYPKYFQK | DIAEPHIPCL | MPEYFEPQIK | DISEAALKER | IELRKVKASV | DMFDQLLQAG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TTVSLETTNS | LLDLLCYFGD | QEPSTDYHFQ | QTEQSEALEV | ENDETSRRKA | GHQFGVTWQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KNNAERIFSL | MPEKNAHSYC | TMIRGMVKHR | AYEQALNLYT | ELLNNRLHAD | VYTFNALTEA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TVCVINGKFE | EKWSKIQELL | RHMVAQKVKP | NLQTFNTILK | CLRRFHVFAR | SPALRILREM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KAIGIEPSLA | TYHHIIHVFD | QPGDPLKRSS | FIIYDIMNEL | MGKRFSPKDP | DDDKFFQSAM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SICSSLRDLE | LAYQVHGLLN | TGDNWKFIGP | DHHRNFYYSK | FFDLICLMEQ | IDVTLKWYED |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LIPSVYFPHS | QTLIHLLQAL | DVANRLEMIP | KIWKDSKEYG | HTFRSDLREE | ILKLMARDKH |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PPELQVAFAD | CAADIKSAYE | SQHIRQTAQD | WPATSLYCIA | ILFLRAGRTQ | EAWNMLELFR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KHNKIPRSEL | LNELMDSAKV | SNSPSQAIEV | VELASAFSLP | ICEGLTQRVM | SDFAINQEQK |
| 670 | 680 | ||||
| EALGNLTALT | SDSDTDSSSD | SDSDTSEGK |