Q5R8N4
Gene name |
VPS35L |
Protein name |
VPS35 endosomal protein-sorting factor-like |
Names |
|
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173041 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R8N4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R8N4-F1 | Predicted | AlphaFoldDB |
No variants for Q5R8N4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R8N4 | |||||
No associated diseases with Q5R8N4
No regional properties for Q5R8N4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5R8N4 | |||
Functions
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| endocytic recycling | The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVFPWHSRN | RNYKAEFASC | RLEAVPLEFG | DYHPLKPITV | TESKTKKVNR | KGSTSSTSSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SSSSVVDPLS | SVLDGTDPLS | MFAATADPAA | LAAATDSSRK | KRDRDDNSIV | GSDFEPWANK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RGEILARYTT | TEKLSINLFM | GSEKGKAGTA | TLAMSEKVRT | RLEELDDFEE | GSQKELLNLT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QQDYVNRIEE | LNQSLKDAWA | SDQKVKALKI | VIQCSKLPSD | TSVIQFYPSK | FVLITDILDT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FGKLVYERIF | SMCVDNRSVL | PDHFSPENAN | DTAKETCLNW | FFKIASIREL | IPRFYVEASI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LKCNKFLSKT | GISECLPRLT | CMIRGIGDPL | VSVYARAYLC | RVGMEVAPHL | KETLNKNFFD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FLLTFKQIHG | DTVQNQLVVQ | GVELPSYLPL | YPPAMDWIFQ | CISYHAPEAL | LTEMMERCKK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LGNNALLLNS | VMSAFRAEFI | ATRSMDFIGM | IKECDESGFP | KHLLFRSLGL | NLALADPPES |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DRLQILNEAW | KVITKLKNPQ | DYINCAEVWV | EYTCKHFTKR | EVNTVLADVI | KHMTPDRAFE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DSYPQLQLII | KKVIAHFHDF | SVLLSVEKFL | PFLDMFQKES | VRVEVCKCIM | DAFIKHQQEP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TKDPVILNAL | LHVCKTMHDS | VNALTLEDEK | RMLSYLINGF | IKMVSFGRDF | EQQLSFYVES |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RSMFCNLEPV | LVQLIHSVNR | LAMETRKVMK | GNHSRKTAAF | VRACVAYCFI | TIPSLVGIFT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RLNLYLHSGQ | VALANQCLSQ | ADAFFKAAIS | LVPEVPKMIN | IDGKMRPSES | FLLEFLCNFF |
| 790 | 800 | 810 | 820 | 830 | 840 |
| STLLIVPDHP | EHGVLFLVRE | LLNVIQDYTW | EDNSDEKIRI | YTCVLHLLSA | MSQETYLYHI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| DKVDSNDSLY | GGDSKFLAEN | NKLCETVMAQ | ILEHLKTLAK | DEALKRQSSL | GLSFFNSILA |
| 910 | 920 | 930 | 940 | 950 | 960 |
| HGDLRNNKLN | QLSVNLWHLA | QRHGCADTRT | MVKTLEYIKK | QSKQPDMTHL | TELALRLPLQ |
| TRT |