Q5R8E4
Gene name |
RMDN1 (FAM82B) |
Protein name |
Regulator of microtubule dynamics protein 1 |
Names |
RMD-1, Protein FAM82B |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173097 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R8E4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R8E4-F1 | Predicted | AlphaFoldDB |
No variants for Q5R8E4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R8E4 | |||||
No associated diseases with Q5R8E4
6 regional properties for Q5R8E4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 278 - 286 | IPR000629 |
| domain | Helicase, C-terminal | 344 - 506 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 146 - 322 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 141 - 348 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 122 - 150 | IPR014014 |
| domain | DDX52/Rok1, DEAD-box helicase domain | 133 - 336 | IPR044764 |
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
| spindle pole | Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALAARLWRF | LPFRRGAAPG | SLLSAGTSGS | RGHCGPCRLR | GFEVMGNPGT | FKRGLLLSAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SYLGFETYQV | ISQAAVVHAT | AKVEEILEQA | DYLCESGETE | KLYQLLTQYK | ESEDAELLWR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LARASRDVAQ | LSRTSEEEKK | LLVYEALEYA | KRALEKNESS | FAAHKWYAIC | LSDVGDYEGI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KAKIANAYII | KEHFEKAIEL | NPKDATSIHL | MGIWCYTFAE | MPWYQRRIAK | MLFATPPSST |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YEKALSYFHR | AEQVDPNFYS | KNLLLLGKTY | LKLHNKKLAA | FWLMKAKDYP | AHTEEDKQIQ |
| 310 | |||||
| TEAAQLLTSF | SEKN |