Q5R891

PR
Gene name
LNPK
Protein name
Endoplasmic reticulum junction formation protein lunapark
Names
ER junction formation factor lunapark
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100173134
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

120-267 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R891

Entry ID Method Resolution Chain Position Source
AF-Q5R891-F1 Predicted AlphaFoldDB

No variants for Q5R891

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R891

No associated diseases with Q5R891

1 regional properties for Q5R891

Type Name Position InterPro Accession
domain Lunapark domain 256 - 305 IPR019273

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein ; Cytoplasmic side
  • Localizes at endoplasmic reticulum (ER) three-way tubular junctions, which represent crossing-points at which the tubules build a polygonal network
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum tubular network membrane The membrane of the endoplasmic reticulum tubular network.
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
endoplasmic reticulum tubular network maintenance The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
positive regulation of endoplasmic reticulum tubular network organization Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGGLFSRWRT KLSTVEVLES IDKEIQALEE FREKNQRLQK LRVGRLILYS SVLYLFTCLI
70 80 90 100 110 120
VYLWYLPDEF TARLAMTLPF FAFPLIIWSI RTVIIFFFSK RTERNNEALD DLKSQRKKIL
130 140 150 160 170 180
EEVMEKETYK TAKLILERFD PDSKKAKECE PPSAGGAVTA RPGQEIRQRT AAQRNLSPTP
190 200 210 220 230 240
ASPNQGPPPQ VPVSPGPPKD SSAPGGPPER TVTPALSSNV LPRHLGSPAT SVPGMGLHPP
250 260 270 280 290 300
GPPLARPILP RERGALDRIV EYLVGDGPQN RYALICQQCF SHNGMALKEE FEYIAFRCAY
310 320 330 340 350 360
CFFLNPARKT RPQAPRLPEF SFEKRQVVEG SSSVGPLPSG SVLSSDNQFN EESLEQDVLD
370 380 390 400 410 420
NNTEQTDDKI PATEQTNQVI EKASDSEEPE EKQETENEEA SVIETNSTVP GADSIPDPEL
NGESLTAE