Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q5R839

Entry ID Method Resolution Chain Position Source
AF-Q5R839-F1 Predicted AlphaFoldDB

No variants for Q5R839

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R839

No associated diseases with Q5R839

2 regional properties for Q5R839

Type Name Position InterPro Accession
domain SLC41A/MgtE, integral membrane domain 139 - 272 IPR006667-1
domain SLC41A/MgtE, integral membrane domain 353 - 496 IPR006667-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Basolateral cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
basolateral plasma membrane The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.

2 GO annotations of molecular function

Name Definition
magnesium ion transmembrane transporter activity Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.
magnesium:sodium antiporter activity Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).

2 GO annotations of biological process

Name Definition
cellular magnesium ion homeostasis Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell.
cellular response to magnesium ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSKPEPKDV HQLNGTGPSA SPCSSDGPGR EPLAGTSEFL GPDGAGVEVV IESRANAKGV
70 80 90 100 110 120
REEDALLENG SQSNESDDVS TDRGPAPPSP LKETSFSIGL QVLFPFLLAG FGTVAAGMVL
130 140 150 160 170 180
DIVQHWEVFQ KVTEVFILVP ALLGLKGNLE MTLASRLSTA ANIGHMDTPK ELWRMITGNM
190 200 210 220 230 240
ALIQVQATVV GFLASIAAVV FGWIPDGHFS IPHAFLLCAS SVATAFIASL VLGMIMIGVI
250 260 270 280 290 300
IGSRKIGINP DNVATPIAAS LGDLITLALL SGISWGLYLE LNHWRYIYPL VCAFFVALLP
310 320 330 340 350 360
VWVVLARRSP ATREVLYSGW EPVIIAMAIS SVGGLILDKT VSDPNFAGMA VFTPVINGVG
370 380 390 400 410 420
GNLVAVQASR ISTFLHMNGM PGENSEQAPR RCPSPCTTFF SPDVNSRSAR VLFLLVVPGH
430 440 450 460 470 480
LVFLYTISCM QGGHTTLTLI FIIFYMTAAL LQVLILLYIA DWMVHWMWGR GLDPDNFSIP
490 500 510
YLTALGDLLG TGLLALSFHV LWLIGDRDTD VGD