Q5R826
Gene name |
TMEM63A |
Protein name |
CSC1-like protein 1 |
Names |
Transmembrane protein 63A |
Species |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
KEGG Pathway |
pon:100173184 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5R826
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5R826-F1 | Predicted | AlphaFoldDB |
No variants for Q5R826
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5R826 | |||||
No associated diseases with Q5R826
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| lysosomal membrane | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium activated cation channel activity | Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient. |
| nucleic acid binding | Binding to a nucleic acid. |
| osmolarity-sensing cation channel activity | Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDSPFLELW | QSRAVSVREQ | LGLGDRPNDS | YCYNSAKNST | VLQGVTFGGI | PTVLLIDVSC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FLFLILVFSI | IRRRFWDYGR | IALVSEADSE | PRFQRLSSTS | SSGQQDFENE | LGCCPWLTAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRLHDDQILE | WCGEDAIHYL | SFQRHIIFLL | VVVSFLSLCV | ILPVNLSGDL | LDKDPYSFGR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TTIANLQTDN | DLLWLHTIFA | VIYLFLTVGF | MRHHTQSIKY | KEENLVRRTL | FITGLPRDAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KETVESHFRD | AYPTCEVVDV | QLCYNVAKLI | YLCKERKKTE | KSLTYYTNLQ | VKTGQRTLIN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PKPCGQFCCC | EVQGCEWEDA | ISYYTRMKDR | LLERITEEER | HVQDQPLGMA | FVTFQEKSMA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TYILKDFNAC | KCQSLQCKGE | PQPSSHSREL | YTSKWTVTFA | ADPEDICWKN | LSIQGLRWWL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QWLGINFTLF | LGLFFLTTPS | IILSTMDKFN | VTKPIHALNN | PIISQFFPTL | LLWSFSALLP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SIVYYSTLLE | SHWTKSGENQ | IMMTKVYIFL | IFMVLILPSL | GLTSLDFFFR | WLFDKTSSEA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SIRLECVFLP | DQGAFFVNYV | IASAFIGNGM | ELLRLPGLIL | YTFRMIMAKT | AADRRNVKQN |
| 610 | 620 | 630 | 640 | 650 | 660 |
| QAFQYEFGAM | YAWMLCVFTV | IMAYSITCPI | IAPFGLIYIL | LKHMVDRHNL | YFIYLPAKLE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KGIHFAAVNQ | ALAAPILCLF | WLYFFSFLRL | GMKAPATLFT | FLVVLLTILV | CLAHTCFGYF |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KHLSPLNYKT | EEPASDKGSE | AEAHMPPPFT | PYVPRILNGL | ASERTALSPQ | QQQQQTYGAI |
| 790 | 800 | ||||
| HNISGTIPGQ | CLAQSATGSV | AAAPQEA |