Q5R811

PR
Gene name
TXNIP
Protein name
Thioredoxin-interacting protein
Names
Species
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
KEGG Pathway
pon:100174583
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5R811

Entry ID Method Resolution Chain Position Source
AF-Q5R811-F1 Predicted AlphaFoldDB

No variants for Q5R811

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5R811

No associated diseases with Q5R811

2 regional properties for Q5R811

Type Name Position InterPro Accession
domain Orotidine 5'-phosphate decarboxylase domain 5 - 226 IPR001754
active_site Orotidine 5'-phosphate decarboxylase, active site 57 - 70 IPR018089

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cellular response to tumor cell Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
negative regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS
70 80 90 100 110 120
QQCKQTSEYL RYEDTLLLED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC
130 140 150 160 170 180
VDYWVKAFLD RPSQPTQGTK KNFEVVDLVD VNTPDLMAPV SAKKEKKVSC MFIPDGRVSV
190 200 210 220 230 240
SARIDRKGFC EGDEISIHAD FENTCSRIVV PKAAIVARHT YLANGQTKVL TQELSSVRGN
250 260 270 280 290 300
HIISGTCASW RGKSLRVQKI RPSILGCNIL RVEYSLLIYV SVPGSKKVIL DLPLVIGSRS
310 320 330 340 350 360
GLSSRTSSMA SRTSSEMSWV DLNIPDTPEA PPCYMDIIPE DHRLESPTTP LLDDMDGSQD
370 380 390
SPIFMYAPEF KFMPPPTYTE VDPCILNNNV Q